글루타티온

용도자연계에 널리 분포하여 동물, 효소 등 거의 모든 생체 내의 산화환원반응에 중요한 역할을 한다. 일부 미생물의 성장인자이고, 효소 글리옥살라아제의 조효소이며, 또 SH기를 가진 효소(카텝신 등)의 활성화에도 관여한다.

개요Glutathione (GSH) is a tripeptide (γ-glutamylcysteinylglycine) widely distributed in both plants and animals. GSH serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH is also involved in amino acid transport and maintenance of protein sulfhydryl reduction status. The concentration of GSH ranges from a few micromolar in plasma to several millimolar in tissues such as liver.

일반 설명Glutathione (GSH) is the most important nonprotein thiol widely distributed in animal tissues, plants, and microorganisms. GSH is also a key determinant of redox signaling and protection against oxidative stress.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.