hydroxylamine-O-sulfonic acid (HCID 76284)

이름 및 식별자

우선 이름: hydroxylamine-O-sulfonic acid
IUPAC: amino hydrogen sulfate
현지명: 히드록실아민-O-설폰산
영어명: Hydroxylamine-O-sulfonic acid
분자식: H3NO4S
분자량: 113.09

이름 및 동의어

Hydroxylamine-O-sulfonic acid2950-43-8Sulfamic acid N-oxideSulfoperamidic acidPermonosulfamic acidAmidosulfonic peracidHAOSAmidoperoxymonosulfuric acidAminomonopersulfuric acidHydroxylamine-O-sulphonic acidHydroxylaminesulfonic acidSulfuric acid, monoazanyl ester

이름 더 보기

히드록실아민-O-설폰산히드록실아민-O-술폰산HOSAHOSHydroxylaMine-0-sulfonic acidAmino hydrogen sulphateo-hydroxylammoniumsulfonateTBX5

YM8MWJ7XSPDTXSID50883542RefChem:147204DTXCID001023065220-971-6amino hydrogen sulfate(aminooxy)sulfonic acidMFCD00011604

데이터베이스 식별자

CAS: 2950-43-8
PubChem CID: 76284
DTXSID: DTXSID50883542
UNII: YM8MWJ7XSP
EC Number: 220-971-6
Nikkaji: J208.587I

물성

구조 계산 물성

XLogP: -3.9
극성 표면적: 98 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 5
회전 가능 결합 수: 1
무거운 원자 수: 6
형식 전하: 0
복잡도: 104

실험 및 물리화학적 성질

Physical DescriptionBeige hygroscopic powder; [Aldrich MSDS] White hygroscopic solid; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: 210 °C · 210 °C (dec.)(lit.)
끓는 점: 39 °C · 39 °C(Press: 0.4 Torr)
밀도: 2.2 g/cm3 · 2.2 g/cm3 (20℃)
증기압: 0 · 0-53.329Pa at 25-39℃
저장 조건: 2 · 2-8°C
용해도: 675 g/l · 675g/l(느린 분해)
산도 계수 (pKa): -6.47 · -6.47±0.18(Predicted)
물리적 상태: 결정성 분말
색상: 하얀색
수소이온지수(pH): 0.8 · 0.8 (100g/l, H2O, 20℃)
생물학적 소스: rabbit
수용성: 녹는
BRN: 956566 · 956566
InChI: 1S/H3NO4S/c1-5-6(2,3)4/h1H2,(H,2,3,4)
InChIKey: DQPBABKTKYNPMH-UHFFFAOYSA-N
SMILES: NOS(O)(=O)=O
EPA: Hydroxylamine-O-sulfonic acid (2950-43-8)

화학적 성질

white to slightly beige crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 5건

Danger

H302 (70.4%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H318 (67.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H400 (69.8%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H412 (66.7%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P260, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 162 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 3건

Chemical: Hydroxylamine-O-sulfonic acid

Status: Active Update: 10-06-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/12342；Status: Cease Manufacture Update: 17-01-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/22751

Hydroxylamine-O-sulphonic acid: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1건

Causes burns; Inhalation can cause corrosive effects on the upper respiratory tract and lungs; [Aldrich MSDS] Causes burns; Inhalation can cause corrosive effects on the upper respiratory tract and lungs; May cause skin sensitization; [Alfa Aesar MSDS]

Hazard Classes and CategoriesAcute Tox. 4 (70.4%)；Skin Corr. 1B (100%)；Eye Dam. 1 (67.9%)；Aquatic Acute 1 (69.8%)；Aquatic Chronic 3 (66.7%)

독성 정보

Adverse EffectsDermatotoxin - Skin burns.；Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

규제 정보

Regulatory Information · 3건

Chemical: Hydroxylamine-O-sulfonic acid

Status: Active Update: 10-06-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/12342；Status: Cease Manufacture Update: 17-01-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/22751

Hydroxylamine-O-sulphonic acid: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: NC5427000
ridadr: UN 3260 8/PG 3
HS 번호: 28111980
risk_code: 34-50-43-40-22
hazard_code: C,N
safety_code: 26-36/37/39-45-61-28A-27-22
포장분류: III
위험 등급: 8
기존화학 물질: KE-20600
F 고인화성물질: 10-21
위험 참고 사항: Irritant
Hazard Classifications: Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 3Eye Dam. 1Skin Corr. 1B
스토리지 클래스: 8A - Combustible corrosive hazardous materials

화학 및 산업

용도 및 제조

General Manufacturing InformationSulfuric acid, monoazanyl ester: ACTIVE

응용 분야 · 2건

용도Hydroxylamine-O-sulfonic acid is used in the synthesis of quinolones for the benzodiazepine site of GABAA receptors. It is also used as a polymerization catalyst and an amination reagent. It is involved in the preparation of diazene by reacting with an alkali. It is also used in the inhibition of polychlorinated dibenzo-p-dioxins (PCDD) as well as (polychlorinated biphenyl) PCB formation in co-combustion.

일반 설명Hydroxylamine-O-sulfonic acid is a versatile synthetic reagent. It is widely employed as a nucleophile and as an electrophile in various organic syntheses. It can be synthesized by reacting hydroxylamine sulfate with 30% fuming H2SO4.