Dimethylformamide dimethyl acetal (HCID 78373)

개요

N,N-dimethylformamide dimethyl acetal is an acetal obtained by formal condensation of N,N-dimethylformamide with methanol. N,N-dimethylformamide dimethyl acetal is a derivatisation agent used in gas-chromatography applications. It has a role as a chromatographic reagent. It is a tertiary amino compound and an acetal. It is functionally related to a N,N-dimethylformamide.

이름 및 식별자

우선 이름: Dimethylformamide dimethyl acetal
IUPAC: 1,1-dimethoxy-N,N-dimethylmethanamine
현지명: N,N-디메틸포름아마이드 디메틸 아세탈
영어명: N,N-Dimethylformamide dimethyl acetal
분자식: C5H13NO2
분자량: 119.16

이름 및 동의어

N,N-Dimethylformamide dimethyl acetal4637-24-51,1-dimethoxy-N,N-dimethylmethanamineMethanamine, 1,1-dimethoxy-N,N-dimethyl-DMF Dimethyl acetalDimethylformamide-dimethylacetalDMF-DMADMFDMADimethylformamide dimethyl acetalDimethoxy(dimethylamino)methaneDF7CTT5QPHDTXSID3063540

이름 더 보기

N,N-다이메틸폼아마이드다이메틸아세탈N,N-다이메틸포르마미드다이메틸아세탈N,N-디메틸포름아마이드디메틸디메틸아세탈N,N-디메틸포름아마이드디메틸아세탈N,N-다이메틸포르마미드다이메틸아세탈(N,N-DIMETHYLFORMAMIDEDIMETHYLACETAL)N,N-다이메틸폼아마이드 다이메틸 아세탈Dimethoxy-N,N-dimethylmethanamine1,1-dimethoxy-n,n-dimethyl-methanamin(Dimethylamino)dimethoxymethaneDMF-DIMETHYLACETAL1,1-DIMETHOXY-N,N-DIMETHYLMETHYLAMINEN,N-Dimethylformamide dimethylDIMETHYLFORMAMIDEDIMETHYLACETAL

CHEBI:85061RefChem:134349DTXCID8040488225-063-31,1-Dimethoxytrimethylamine(dimethoxymethyl)dimethylaminedimethylformamide dimethylacetalTrimethylamine, 1,1-dimethoxy-

데이터베이스 식별자

CAS: 4637-24-5
PubChem CID: 78373
DTXSID: DTXSID3063540
ChEBI: CHEBI:85061
UNII: DF7CTT5QPH
EC Number: 225-063-3
Nikkaji: J24.180F

물성

구조 계산 물성

XLogP: 0.2
극성 표면적: 21.7 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 3
회전 가능 결합 수: 3
무거운 원자 수: 8
형식 전하: 0
복잡도: 52.4

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Other Nitrogen Compounds

Vapor Pressure30.0 [mmHg]

Physical DescriptionColorless liquid with a rancid odor; [BASF MSDS]

물리화학적 성질

녹는점: -85 °C · -85°C
끓는 점: 102 · 102-103 °C/720 mmHg (lit.)
밀도: 0.897 g/mL · 0.897 g/mL at 25 °C (lit.)
증기압: 34.5 hPa · 34.5hPa at 20℃
굴절률: 20 · n20/D 1.396(lit.)
인화점: 45 °F · 45 °F
저장 조건: 30 °C · Store below +30°C.
용해도: 대부분의 유기용매와 섞일 수 있습니다.
물리적 상태: 고체
산도 계수 (pKa): 5 · 5.00±0.50(Predicted)
색상: 흰색에서 황백색까지
수소이온지수(pH): 7 · 7 (H2O)
폭발한계: 1.3 · 1.3-17.7%(V)
수용성: 가수 분해
BRN: 506020 · 506020
InChI: 1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3
InChIKey: ZSXGLVDWWRXATF-UHFFFAOYSA-N
SMILES: COC(OC)N(C)C
LogP: 0.75 · 0.750 (est)
NIST: 1 · Methanamine, 1,1-dimethoxy-N,N-dimethyl-(4637-24-5)
EPA: 1 · Methanamine, 1,1-dimethoxy-N,N-dimethyl- (4637-24-5)

화학적 성질

clear colourless liquid

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 230 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 3건

Chemical: Methanamine, 1,1-dimethoxy-N,N-dimethyl-

Status: Active Update: 13-01-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/11035

Dimethylformamide-dimethylacetal: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryAn irritant; May cause skin sensitization; Harmful by inhalation; [BASF MSDS] See Dimethylformamide. See 1,1-Dimethoxyethane.

Hazard Classes and CategoriesFlam. Liq. 2 (100%)

독성 정보

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.

Toxicity DataLC50 (rat) = 12,160 mg/m3/4hr

안전 데이터

wgk: 1
tsca: TSCA listed
ridadr: UN 3271 3/PG 2
독성: LD50 orally in Rabbit: > 5000 mg/kg
HS 번호: 29225000
risk_code: 11-22-36/37/38-36/38-20-20/21/22-10-52
hazard_code: F,Xn,Xi
safety_code: 16-26-36/37-36/37/39-33-29-7/9
포장분류: II
위험 등급: 3
기존화학 물질: KE-11054
F 고인화성물질: 21
자연 발화 온도: 155 °C
Hazard Classifications: Acute Tox. 4 InhalationEye Dam. 1Flam. Liq. 2Skin Sens. 1
스토리지 클래스: 3 - Flammable liquids

화학 및 산업

용도 및 제조

UsesUsed as an intermediate; [BASF MSDS]

General Manufacturing InformationMethanamine, 1,1-dimethoxy-N,N-dimethyl-: ACTIVE

응용 분야 · 2건

용도N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates.

일반 설명Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.

상·하류 제품 정보

상류 원료

MethanaMiniuM,메톡시디메틸-,메틸설페이트(1:1)메틸산 나트륨 N,N-다이메틸폼아마이드

하류 제품

(5-(Trifluoromethyl)-1-methyl-1H-pyrazol-4-yl)methanamine (1-tert-Butyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanol 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 5-메틸-1-페닐-1H-피라졸-4-카르복실산 (5-(Trifluoromethyl)-1-phenyl-1H-pyrazol-4-yl)methanol 1-페닐-5-(트리플루오로메틸)-1H-피라졸-4-카르복시산 1-tert-Butyl 6-methyl 3-formyl-1H-indole-1,6-dicarboxylate Ethyl 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylate 3-Bromochromone 5-(Trifluoromethyl)-1-phenyl-1H-pyrazole-4-carbonitrile 5-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carbonyl chloride Methyl 4-amino-6-indolecarboxylate

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

南京一化生物科技有限公司13429882898; 13429882898

上海泰矶林实业有限公司02150630626 17717886015 · [email protected]

추가 설명

정의ChEBI: An acetal obtained by formal condensation of N,N-dimethylformamide with methanol. N,N-dimethylformamide dimethyl acetal is a derivatisation agent used in gas-chromatography applica ions

연결된 노트

불러오는 중…

N,N-디메틸포름아마이드 디메틸 아세탈

기본 정보

개요