Pentylamine (HCID 8060)

개요

N-amylamine appears as a clear colorless liquid with an ammonia-like odor. Irritates the eyes and respiratory system. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a corrosion inhibitor, solvent, flotation agent and in the manufacture of other chemicals.

이름 및 식별자

우선 이름: Pentylamine
IUPAC: pentan-1-amine
현지명: 노르말펜틸아민
영어명: Amylamine
분자식: C5H13N
분자량: 87.16

이름 및 동의어

AmylaminePentylamine110-58-7pentan-1-amine1-Aminopentane1-PentylamineN-AMYLAMINE1-Pentanaminen-PentylamineMonoamylamineNorleucamineE05QM3V8EF

이름 더 보기

N-아밀아민노르말펜틸아민아밀아민PentylaminAMYLAMINESAmylaminAMINE C5

NSC-7906DTXSID0021919FEMA NO. 4242CHEBI:74848RefChem:171523DTXCID801919203-780-2932-628-4

데이터베이스 식별자

CAS: 110-58-7
PubChem CID: 8060
DTXSID: DTXSID0021919
ChEBI: CHEBI:74848
UNII: E05QM3V8EF
EC Number: 203-780-2、932-628-4、935-734-9
Nikkaji: J1.978J

물성

구조 계산 물성

XLogP: 1.5
극성 표면적: 26 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 1
회전 가능 결합 수: 3
무거운 원자 수: 6
형식 전하: 0
복잡도: 19.9

실험 및 물리화학적 성질

Chemical Classes · 2건

Nitrogen Compounds -> Amines, Aliphatic

Corrosives

DrugsPharmaceuticals -> Listed in ZINC15

SpringerMaterials PropertiesBoiling point

Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food

Density · 2건

0.7547 (NTP, 1992) - Less dense than water; will float

0.750-0.759

Flavoring AgentsEU Flavoring substances

물리화학적 성질

녹는점: 55 °C · −55 °C(lit.)
끓는 점: 104 °C · 104 °C(lit.)
밀도: 0.752 g/mL · 0.752 g/mL at 25 °C(lit.)
증기 밀도: 3.01 · 3.01 (vs air)
증기압: 120.9 hPa · 120.9 hPa (47 °C)
FEMA: 4242 · 4242 | PENTYLAMINE
굴절률: 20 · n20/D 1.411(lit.)
인화점: 42 °F · 42 °F
저장 조건: Flammables area
용해도: 알코올, 에테르에 용해됩니다.
산도 계수 (pKa): 10.63 · 10.63(at 25℃)
물리적 상태: 액체
색상: 투명하고 무색에서 아주 약간 노란색을 띤다.
냄새: 0.1 % · 프로필렌 글리콜 중 0.10%. 암모니아성 비린내
냄새 유형: 비린내
생물학적 소스: synthetic
폭발한계: 2.2 · 2.2-22%(V)
수용성: 녹는
비열: 2.5 J/ · Cp(liquid): 2.5 J/(g·K), at 25℃
Merck: 14 · 14,598
JECFA Number: 1585 · 1585
BRN: 505953 · 505953
Henry's Law Constant: 4.3 · 4.3×10-1 mol/(m3Pa) at 25℃, Brockbank (2013)
Dielectric constant: 4.6 · 4.6(22℃)
주요 응용: 향료 및 향
InChI: 1S/C5H13N/c1-2-3-4-5-6/h2-6H2,1H3
InChIKey: DPBLXKKOBLCELK-UHFFFAOYSA-N
SMILES: CCCCCN
LogP: 1.49 · 1.49
NIST: 1 · 1-Pentanamine(110-58-7)
EPA: Amylamine (110-58-7)

화학적 성질

n-Amylamine is a strong base in aqueous solutions and organic solvents that readily forms salts with acids.

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 171 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

유해성 정보

Regulatory Information · 5건

Chemical: 1-Pentanamine

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Status: Active Update: 09-02-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/11243

Amylamine: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelFlammable Liquid Corrosive

Fire Hazards · 2건

Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

· Flammable/combustible material.

Health Hazards · 2건

Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

· May cause toxic effects if inhaled or ingested.

Hazards Summary · 1건

Corrosive to skin; [Quick CPC] A severe irritant; [NTP] Safe when used as a flavoring agent in food; [JECFA] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS]

DOT ID and Guide1106 132

안전 및 보호

Fire FightingExcerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

Accidental Release Measures · 2건

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

First Aid · 2건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

General First Aid:

Exposure Control and Personal Protection· Wear positive pressure self-contained breathing apparatus (SCBA).

Nonfire Spill ResponseExcerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

Isolation and Evacuation · 2건

Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

Immediate precautionary measure

독성 정보

Adverse EffectsDermatotoxin - Skin burns.

Toxicity DataLCLo (rat) = 2,000 ppm/4hr

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: SC0300000
ridadr: UN 1106 3/PG II/III (AMYLAMINE)
독성: LD50 orally in Rabbit: 470 mg/kg LD50 dermal Rabbit 1120 mg/kg
HS 번호: 29211990
risk_code: 11-22-34-42/43-20/21/22-52/53
hazard_code: F,C
safety_code: 16-26-36/37/39-45-33-61
포장분류: II
위험 등급: 3
기존화학 물질: KE-28062
F 고인화성물질: 34
자연 발화 온도: 305 °C
Hazard Classifications: Acute Tox. 4 DermalAcute Tox. 4 OralAquatic Chronic 3Eye Dam. 1Flam. Liq. 2Skin Corr. 1B
스토리지 클래스: 3 - Flammable liquids

화학 및 산업

용도 및 제조

UsesUsed as a chemical intermediate, solvent, gasoline additive, and in corrosion inhibitors, dyestuffs, flotation agents, rubber chemicals, insecticides, and pharmaceuticals; [NTP]

Use Classification · 3건

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

General Manufacturing Information1-Pentanamine: ACTIVE

응용 분야 · 2건

용도Amylamine is a general reagent used in functionalizing the target molecules with pentyl chain. It has also been used as a cosurfactant to increase the phase stability of the bilayer systems.

일반 설명A clear colorless liquid with an ammonia-like odor. Flash point 30°F. Irritates the eyes and respiratory system. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a corrosion inhibitor, solvent, flotation agent and in the manufacture of other chemicals.

제조 방법 · 1건

생산 방법n-Amylamine is primarily produced by the amination of alkyl halides rather than using alcohol. This reaction is carried out at a temperature of 300-500°C and a pressure of 790-3550 kPa. Alternatively, n-amylamine can be produced from the reaction of amyl chlorides with ammonia. This procedure also produces small amounts of amylenes and amyl alcohol which can be removed by steam distillation (Schweizer et al 1978).