3,4-dihydro-2H-pyran (HCID 8080)

개요

Dihydro-2h-pyran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Vapors heavier than air.

이름 및 식별자

우선 이름: 3,4-dihydro-2H-pyran
IUPAC: 3,4-dihydro-2H-pyran
현지명: 3,4-다이하이드로피란
영어명: 3,4-Dihydro-2H-pyran
분자식: C5H8O
분자량: 84.12

이름 및 동의어

3,4-Dihydro-2H-pyran110-87-2DIHYDROPYRAN3,4-Dihydropyran2,3-Dihydro-4H-pyran2H-3,4-Dihydropyran5,6-Dihydro-4H-pyran2H-Pyran, 3,4-dihydro-delta2-DihydropyranPyran, dihydro-DTXSID6041426T6V9N71IHX

이름 더 보기

2,3-다이하이드로피란2,3-디하이드로피란2,3-디히드로피란3,4-다이하이드로피란DHP3,4-Dihydro-2H-pyraneDIHYDROPYRANE3,4-Dihydro-2-pyran3,4-dihydro-2h-pyra

NSC-57860NSC-73472DTXCID4021426RefChem:910852,3-DIHYDRO-GAMMA-PYRAN203-810-4Dihydro-2H-pyran2,3-Dihydropyran

데이터베이스 식별자

CAS: 110-87-2、25512-65-6、3174-74-1
PubChem CID: 8080
DTXSID: DTXSID6041426
ChEMBL: CHEMBL3184439
UNII: T6V9N71IHX
EC Number: 203-810-4
Nikkaji: J43.463I

물성

구조 계산 물성

XLogP: 0.7
극성 표면적: 9.2 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 1
회전 가능 결합 수: 0
무거운 원자 수: 6
형식 전하: 0
복잡도: 57

실험 및 물리화학적 성질

Chemical Classes · 2건

Other Classes -> Ethers, Other

Flammable agents - 3rd degree

SpringerMaterials PropertiesCoriolis coupling

LogP0.69

Density0.922 @ 19°C

Flash Point0 °F (NFPA, 2010)

Physical Description · 3건

Dihydro-2h-pyran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Vapors heavier than air.

Liquid

Clear colorless liquid with an ethereal odor; [CAMEO] Unpleasant odor; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: -70 °C · -70 °C (lit.)
끓는 점: 86 °C · 86 °C (lit.)
밀도: 0.922 g/mL · 0.922 g/mL at 25 °C (lit.)
증기 밀도: 2.9 · 2.9 (vs air)
증기압: 77.8 hPa · 77.8 hPa (20 °C)
굴절률: 20 · n20/D 1.440(lit.)
인화점: 4 °F · 4 °F
저장 조건: 30 °C · Store below +30°C.
용해도: 7.7 g/L · 7.7g/L
물리적 상태: 액체
색상: 무색~황색으로 투명함
수소이온지수(pH): 7 · 7 (5g/l, H2O, 20℃)
폭발한계: 1.1 · 1.1-13.8%(V)
수용성: 20 g/L · 20g/L(20℃)
BRN: 103493 · 103493
안정성: 휘발성 물질
InChI: 1S/C5H8O/c1-2-4-6-5-3-1/h2,4H,1,3,5H2
InChIKey: BUDQDWGNQVEFAC-UHFFFAOYSA-N
SMILES: C1COC=CC1
LogP: 0.69 · 0.690
NIST: 2 H-Pyran, · 2H-Pyran, 3,4-dihydro-(110-87-2)
EPA: 2 H-Pyran, · 2H-Pyran, 3,4-dihydro- (110-87-2)

화학적 성질

colorless to light yellow liqui

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P272, P280, P302+P352, P303+P361+P353, P305+P351+P338, P321, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 180 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

유해성 정보

Regulatory Information · 5건

Chemical: 2H-Pyran, 3,4-dihydro-

2H-Pyran, 3,4-dihydro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2H-Pyran, 3,4-dihydro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 29-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12042

2H-Pyran, 3,4-dihydro-: HSNO Approval: HSR001129 Approved with controls

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelFlammable Liquid

Fire Hazards · 2건

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Health Hazards · 2건

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

· Inhalation or contact with material may irritate or burn skin and eyes.

Hazards SummaryA skin and strong eye irritant; [Alfa Aesar MSDS]

DOT ID and Guide2376 127

안전 및 보호

Fire FightingExcerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

Accidental Release Measures · 2건

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

First Aid · 2건

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

General First Aid:

Exposure Control and Personal Protection· Wear positive pressure self-contained breathing apparatus (SCBA).

Nonfire Spill ResponseExcerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

Isolation and Evacuation · 2건

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

Immediate precautionary measure

독성 정보

Toxicity DataLC50 (rat) > 10,700 mg/m3/4hr

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: UP7700000
ridadr: UN 2376
독성: LD50 orally in Rabbit: > 4000 mg/kg
HS 번호: 29329995
risk_code: 11-36/37/38-36/38-19
hazard_code: F,Xi
safety_code: 16-26-36-37/39-33-7/9
포장분류: II
위험 등급: 3
기존화학 물질: 2012-3-5381
위험 참고 사항: Highly Flammable/Irritant
자연 발화 온도: 240 °C
Hazard Classifications: Aquatic Chronic 3Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2Skin Sens. 1B
스토리지 클래스: 3 - Flammable liquids

화학 및 산업

용도 및 제조

UsesPermitted for use as an inert ingredient in non-food pesticide products; [EPA] Used in organic syntheses; [REPROTOX]

U.S. Production2023: 75,000 - <500,000 lb

Industry UsesIntermediate

General Manufacturing Information · 2건

All Other Basic Organic Chemical Manufacturing

2H-Pyran, 3,4-dihydro-: ACTIVE

응용 분야 · 1건

용도Widely used hydroxyl-protecting reagent3,4-Dihydro-2H-pyran is used as a hydroxyl-protecting reagent in organic synthesis. It acts as an intermediate in synthetic chemistry. It is used to protect various reactive functional groups. It is involved in the polymerization reaction either alone or with unsaturated compound and finds application in polymer industries. Further, it is employed in the preparation of bicyclic compounds of epoxide-fused, halo compounds and allenic alcohols.