숙신이미딜6-(비오틴아미도)헥사노에이트

Nhs-LC-biotin

HCID 83874CAS 72040-63-2

부분 구조 검색 유사 구조 찾기

기본 정보

표준 SMILES: O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NCCCCCC(=O)ON1C(=O)CCC1=O
InChIKey: UVGHPGOONBRLCX-NJSLBKSFSA-N
분자식: C20H30N4O6S
평균 분자량: 454.5 g/mol
단동위원소 질량: 454.18860568

이름 및 식별자

우선 이름: Nhs-LC-biotin
IUPAC: (2,5-dioxopyrrolidin-1-yl) 6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoate
현지명: 숙신이미딜6-(비오틴아미도)헥사노에이트
영어명: Succinimidyl 6-(biotinamido)hexanoate
분자식: C20H30N4O6S
분자량: 454.54

이름 및 동의어

Succinimidyl 6-(biotinamido)hexanoateNhs-LC-biotinRefChem:853804615-709-672040-63-22,5-Dioxopyrrolidin-1-yl 6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoateBACHSSuccinimidyl-6-(biotinamido) HexanoateBiotin-X, succinimidyl esterBiotin-C5-NHS EsterMFCD00065502(+)-Biotin-LC-NHS Ester

이름 더 보기

숙신이미딜6-(비오틴아미도)헥사노에이트BIOTIN-X-NHSBiotin-LC-NHSBIOTIN-X, SENHS-X-BiotinD-BiotiamideBIOTIN-LC-OSUBiotin-NHS LCNHS-Biotin LC

N-Succinimidyl 6-BiotinamidohexanoateSuccinimidyl-6-biotinamide hexanoateBiotinamidohexanoic acid N-hydroxysuccinimide ester(2,5-dioxopyrrolidin-1-yl) 6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoateBiotin-amidocaproate-N-hydroxysuccinimide esterBiotinyl-6-aminocaproic acid N-hydroxysuccinimide esterC20H30N4O6SBiotinyl-epsilon-aminohexanoic acid N-hydroxysuccinimide ester

데이터베이스 식별자

CAS: 72040-63-2
PubChem CID: 83874
DTXSID: DTXSID90992728
EC Number: 615-709-6
Nikkaji: J671.769A

물성

구조 계산 물성

XLogP: 0.1
극성 표면적: 159 Å²
수소 결합 공여자 수: 3
수소 결합 수용자 수: 7
회전 가능 결합 수: 13
무거운 원자 수: 31
형식 전하: 0
복잡도: 702

물리화학적 성질

녹는점: 169 · 169-171 °C
밀도: 1.35 · 1.35±0.1 g/cm3(Predicted)
저장 조건: -20 °C · -20°C
용해도: 2 O: · H2O: 초음파 처리 시 '2 mg/mL
물리적 상태: 가루
산도 계수 (pKa): 13.9 · 13.90±0.40(Predicted)
색상: 흰색에서 황백색까지
수용성: 2 O: · H2O: ≤2mg/mL (with sonication)DMF: 50mg/mL (Stable up to 2 months in dry DMF.)
BRN: 3577403 · 3577403
안정성: 수분에 민감한
InChIKey: UVGHPGOONBRLCX-NJSLBKSFSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCCCCNC(=O)CCCC[C@H]1[C@@]2([H])NC(=O)N[C@@]2([H])CS1

화학적 성질

Succinimidyl 6-(biotinamido)hexanoate is White Solid

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

유해성 정보

Hazard Classes and CategoriesAcute Tox. 4 (100%)

안전 데이터

wgk: 3
HS 번호: 29349990
safety_code: 24/25
F 고인화성물질: 10-21
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야 · 1건

용도Succinimidyl 6-(biotinamido)hexanoate is a biotinylation reagent incorporating an aminocaproyl “spacer”. This can reduce the steric hindrance in binding avidin to some biotinylated compounds when used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin Capture System. This system avoids the direct interaction of a captured antibody with solid surfaces, such as plastics, which may reduce antigenicity. It has also been used to enhance the detection of DNA on nitrocellulose. Has also been used as a cell surface labelling reagent