Malic acid, disodium salt

HCID 8736CAS 22798-10-3

기본 정보

표준 SMILES
O=C([O-])CC(O)C(=O)[O-].[Na+].[Na+]
InChIKey
WPUMTJGUQUYPIV-UHFFFAOYSA-L
분자식
C4H4Na2O5
평균 분자량
178.05 g/mol
단동위원소 질량
177.98541179

개요

On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes that Malic Acid and Sodium Malate are safe for use as pH adjusters in cosmetic formulations. The Expert Panel determined that the data are insufficient to determine the safety of these ingredients for any other functions.

이름 및 식별자

우선 이름
Malic acid, disodium salt
IUPAC
disodium;2-hydroxybutanedioate
영어명
DL-Malic acid disodium salt
분자식
C4H4Na2O5
분자량
178.05

이름 및 동의어

Malic acid, disodium saltRefChem:887666Sodium malate676-46-0Disodium malateDL-Malic acid disodium saltdisodium 2-hydroxybutanedioateDisodium DL-malate22798-10-3disodium;2-hydroxybutanedioateSODIUM DL-MALATESodium 2-hydroxysuccinate
이름 더 보기
DISODIUM DL-MALATE HYDRATEMALIC ACID, SODIUMDI-SODIUM DL-MALATEDL-MALIC ACID SODIUMMalicaciddisodiumsaltdl-malic acid disodiumDl-MalicAcid,SodiumSaltSODIUM DL-MALATE HYDRATEDI-SODIUM MALATE 0.5-WATER
Sodium DL-maleateButanedioic acid, hydroxy-, disodium saltDTXSID7046831malic acid sodium saltMFCD00012466L-HYDROXYBUTANEDIOICACIDDISODIUMSALT2EFF9N315F63474-37-3

데이터베이스 식별자

CAS
22798-10-3、40520-93-2、676-46-0
PubChem CID
8736
DTXSID
DTXSID7046831
ChEMBL
CHEMBL182856
UNII
2EFF9N315F
EC Number
211-627-6、254-952-9、866-020-4
Nikkaji
J3.317K

물성

구조 계산 물성

극성 표면적
100 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
5
회전 가능 결합 수
1
무거운 원자 수
11

실험 및 물리화학적 성질

Cosmetics · 2건

Cosmetic ingredients (Sodium Malate) -> CIR (Cosmetic Ingredient Review)

Humectant; Skin conditioning

SolubilityFreely soluble in water
Physical DescriptionWhite crystalline powder or lumps

물리화학적 성질

녹는점
300 °C · >300 °C(lit.)

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 45.8% (65 of 142) of reports.

Warning

H315 (41.5%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 142 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 100% (37 of 37) of all reports.

유해성 정보

Regulatory Information · 2건

Chemical: Butanedioic acid, hydroxy-, disodium salt

Disodium malate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Butanedioic acid, hydroxy-, disodium salt: Human health tier I assessment
Hazard Classes and Categories · 3건

Skin Irrit. 2 (41.5%)

Skin Irrit. 2 (100%)

Not Classified

독성 정보

Toxicity Summary · 2건

On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes that Malic Acid and Sodium Malate are safe for use as pH adjusters in cosmetic formulations. The Expert Panel determined that the data are insufficient to determine the safety of these ingredients for any other functions.

Safe for use in cosmetics, with qualifications

안전 데이터

wgk
3
rtecs
ON7730000

화학 및 산업

용도 및 제조

UsesCIR ingredient: Sodium Malate
Use Classification · 4건

Food additives

Flavouring Agent -> FLAVOURING_AGENTFood Additives -> ACIDITY_REGULATOR -> JECFA Functional Classes

Flavouring Agent -> FLAVOURING_AGENTFood Additives -> ACIDITY_REGULATOR -> JECFA Functional Classes

Cosmetics -> Humectant; Skin conditioning

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
上海哲研生物科技有限公司021-18017610038 18017610038 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]

관련 반응

5건

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