시트로넬롤

Cosmetics ingredient -> Base; Flavor; Fragrance; Moisturizing/Humectant; Other (Specify)

Masking

Fragrance substance (Citronellol) -> IFRA amendment 49

Fragrance Ingredient (6-Octen-1-ol, 3,7-dimethyl-,(+/-)-) -> IFRA transparency List

Fragrance Ingredient (dl-Citronellol) -> IFRA transparency List

Fresh rosy odor

Rose odor

Bitter taste /d-Citronellol/; sweet, peach-like flavor /l-citronellol/

Taste characteristics at 20 ppm: floral, rose, sweet and green with fruity citrus nuances

0.8550 g/cu cm at 20 °C

0.850-0.860

In water, 200 mg/L at 25 °C

In water, 307 mg/L at 25 °C; 300 mg/L at 20 °C

Soluble in fixed oils, propylene glycol; insoluble in glycerin

Miscible in ethanol and ether /(+)-citronellol/; very soluble in ethanol and ether /(-)-citronellol/

Insoluble in glycerol; slightly soluble in water; soluble in most fixed oils, propylene glycol

soluble (in ethanol)

Warning

H315 (95.7%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P272, P273, P280, P302+P352, P305+P351+P338, P321, P332+P317, P333+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 1657 reports by companies from 29 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

Chemical: 6-Octen-1-ol, 3,7-dimethyl-

Regulation (EC) No 1831/2003 (amended)

6-Octen-1-ol, 3,7-dimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 6-Octen-1-ol, 3,7-dimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 02-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14242

Citronellol: Does not have an individual approval but may be used under an appropriate group standard

Causes degenerative changes to brain, dermatitis, changes in liver and kidney weights, and somnolence in acute oral studies of rats; Causes alteration of classical conditioning and abnormal liver function tests in 100-day inhalation studies of rats; [RTECS] A moderate skin irritant; Category members and supporting chemicals demonstrate skin sensitization in humans and mice; No systemic toxicity in 112-day and 17-week oral studies of rats at the highest tested doses (approximately 500 mg/kg/day); Mortality, stomach lesions, and cytoplasmic vacuolization (lipidosis) of the liver, kidney, and myocardium in 13-week oral study of mice (LOAEL of 2,000 mg/kg/day); [EPA ChAMP: Terpenoid Primary Alcohols and Related Esters - 2009] Fragrance ingredient that is a recognized contact allergen in consumers; [EC: SCCNFP] Generally regarded as safe (GRAS) by the FDA; [ToxPlanet: EPA BRADs] Safe when used as a flavoring agent in food; [JECFA] An irritant; [Acros Organics MSDS]

Citronellol is a food additive permitted for direct addition to food for human consumption as a synthetic flavoring substance and adjuvant in accordance with the following conditions: a) they are used in the minimum quantity required to produce their intended effect, and otherwise in accordance with all the principles of good manufacturing practice, and b) they consist of one or more of the following, used alone or in combination with flavoring substances and adjuvants generally recognized as safe in food, prior-sanctioned for such use, or regulated by an appropriate section in this part.

Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. (a) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils. Citronellol is included on this list. Limit: When ready for use, the end-use concentration is not to exceed 100 ppm.

An exemption from the requirement of a tolerance is established for residues of the biochemical pesticide citronellol in or on all food commodities.

Skin Irrit. 2 (100%)

Skin Irrit. 2 (95.7%)

...moderate eye irritation...

/Skin/ moderately irritating.

Wear self-contained breathing apparatus for firefighting if necessary.

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging Dispose of as unused product.

Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. (a) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils. Citronellol is included on this list. Limit: When ready for use, the end-use concentration is not to exceed 100 ppm.

An exemption from the requirement of a tolerance is established for residues of the biochemical pesticide citronellol in or on all food commodities.

Skin protection: Handle with gloves.

Eye/face protection: Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Body Protection: Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

LC50; Species: Leuciscus idus (Golden orfe); Conditions: static; Concentration: >10 mg/L for 96 hr

EC50; Species: Selenastrum subspicatus (Green algae); Concentration: 2.38 mg/L for 72 hr; Effect: growth /Conditions of bioassay not specified in source examined/

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 94(SRC), determined from a structure estimation method(2), indicates that citronellol is expected to have high mobility in soil(SRC). Volatilization of citronellol from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.1X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 0.02 mm Hg(3), and water solubility, 200 mg/L(4). Even though the vapor pressure is low environmentally at standard temperature and pressure, there is a detectable odor; therefore, citronellol may volatilize from dry soil(SRC). An 80-90% of Theoretical BOD using activated sludge in the OECD 301F test(5) suggests that biodegradation is an important environmental fate process in soil(SRC). Citronellol was also classified as readily biodegradable by the results of the OECD 301C test (modified MITI) with 65% degradation in 4 weeks(6) and by a DOC Method F test (100% biodegradation in 15 days)(6). Citronellol absorbs at wavelengths >290 nm(7) and, therefore, may be susceptible to direct photolysis on soil surfaces exposed to sunlight(SRC).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 94(SRC), determined from a structure estimation method(2), indicates that citronellol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 2.1X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 0.02 mm Hg(4), and water solubility, 200 mg/L(5). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 2.4 and 21 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 177(SRC), from its log Kow of 3.91(7) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is high(SRC). An 80-90% of Theoretical BOD using activated sludge in the OECD 301F test(8) suggests that biodegradation is an important environmental fate process in water(SRC). Citronellol was also classified as readily biodegradable by the results of the OECD 301C test (modified MITI) with 65% degradation in 4 weeks(9) and by a DOC Method F test (100% biodegradation in 15 days)(9). Citronellol is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(3). Citronellol is an olefin and olefins in surface waters exposed to sunlight react with photo-oxidants (such as hydroxyl radicals, peroxy radicals and singlet oxygen) with a half-life on the order of 25 days(10).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), citronellol, which has a vapor pressure of 0.02 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase citronellol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 2.3 hours(SRC), calculated from its rate constant of 1.70X10-10 cu cm/molecule-sec at 24 deg(3). Citronellol is also degraded in the atmosphere by reaction with ozone and nitrate radicals. The half-life for the reaction with ozone is estimated to be 1.1 hours(SRC), calculated from its rate constant of 2.4X10-16 cu cm/molecule-sec at 24 °C(3). The half-life for the reaction with nitrate radicals is estimated to be 4 minutes(SRC), calculated from its rate constant of 1.21X10-11 cu cm/molecule-sec at 24 °C(4). The nitrate radical (NO3) is the dominant atmospheric oxidant during the night-time in most atmospheric environments(5), therefore, night-time degradation appears to be a major fate process for citronellol(SRC). Citronellol absorbs at wavelengths >290 nm(6) and, therefore, may be susceptible to direct photolysis by sunlight(SRC).

IDENTIFICATION AND USE: Citronellol has been found in nature, and it has been reported in about 70 essential oils. It is registered for pesticide use in the USA but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. It is also used in perfumery. HUMAN EXPOSURE AND TOXICITY: Adult male volunteers with no known allergic reactions were patch-tested on their back for 48 hr with 32% citronellol. After 48 hr, patches were removed and the skin was cleaned of any residual test material. Moderate irritation was observed. A patch test using a 1% concentration of citronellol in acetone gave a positive reaction in subjects allergic to citronella oil. ANIMAL STUDIES: Citronellol applied full strength to intact or abraded rabbit skin for 24 hr under occlusion was moderately irritating. Severe irritation was observed in rabbits and guinea pigs exposed to 100% compound (unoccluded) for 24, 48 or 72 hr. Citronellol was not mutagenic when tested in Salmonella typhimurium strains TA98 and TA100 in the presence and absence of metabolic activation. ECOTOXICITY STUDIES: Golden Orfe (Leuciscus idus) were exposed to this chemical under static conditions for 96 hours. No mortalities were seen in the control and 4.64 mg/L groups. At 10 mg/L, apathy was noted up to 24 hr, but no mortalities were noted at 96 hr. At 21.5, 46.4 and 100 mg/L, 100% mortality was seen 1 hour after exposure.

/AQUATIC SPECIES/ Golden Orfe (Leuciscus idus) were exposed to nominal concentrations of 0, 4.64, 10, 21.5, 46.4 or 100 mg/L of this chemical under static conditions for 96 hours. No mortalities were seen in the control and 4.64 mg/L groups. At 10 mg/L, apathy was noted up to 24 hours, but no mortalities were noted at 96 hours. At 21.5, 46.4 and 100 mg/L, 100% mortality was seen 1 hour after exposure. 96-hr LC50 > 10 mg/L

(+)-Citronellol occurs in natural oils from Boronia citriodora (total citronellol content about 80%) and Eucalyptus citriodora (total citronellol content 15-20%)(1); (-)-Citronellol is the predominant enantiomer in geranium and rose oils, both of which may contain up to 50% citronellols(1). Citronellol has reported to occur in about 70 essential oils(2). It reportedly occurs in guava fruit, orange, bilberry, blackcurrant, nutmeg, ginger, corn, mint oil, mustard, hop oil, tea, coriander seed, and cardamom(2). Essential oils from twigs and needles of the Balkan pine (Pinus peuce Gris.) grown in northern Greece was found to contain citronellol in the twig oil (12.48% of total) and needle oil (13.42% of total)(3). Trace concentrations of citronellol (<20 ug/kg) were detected in the flowers of Japan honeysuckle (Lonicera japonica)(4). Citronellol has been detected in tobacco(5). The essential oil of rose water, derived from Rosa damascena Mill. from northern India, contained citronellol at concentrations of 15.9-35.3%(6).

Citronellol detections in plants(1).[Table#6301]

EPA has released the first beta version (version 0.5) of the Interactive Chemical Safety for Sustainability (iCSS) Dashboard. The beta version of the iCSS Dashboard provides an interactive tool to explore rapid, automated (or in vitro high-throughput) chemical screening data generated by the Toxicity Forecaster (ToxCast) project and the federal Toxicity Testing in the 21st century (Tox21) collaboration. /The title compound was tested by ToxCast and/or Tox21 assays; Click on the "Chemical Explorer" button on the tool bar to see the data./[USEPA; ICSS Dashboard Application; Available from, as of April 22, 2015: http://actor.epa.gov/dashboard/]

Citronellol is emitted into the ambient air from household products such as pine-oil based cleaners, orange oil-based degreasers and plug-in air fresheners(1). Citronellol was detected in volatile emissions from the leaves of Eucalyptus citriodora(2).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of citronellol can be estimated to be 94(SRC). According to a classification scheme(2), this estimated Koc value suggests that citronellol is expected to have high mobility in soil.

Citronellol is widespread in nature in both enantiomeric forms, the richest sources being rose and geranium(1). Citronellol is reported to occur in about 70 essential oils(2). Citronellol has been detected and quantified in numerous plant species(3).

/HUMAN EXPOSURE STUDIES/ The fragrance mix (FM I), established in 1977, detects the majority, but not all cases of contact allergy to fragrances. Based on European research 2002/2003, fragrance mix II (FM II) was developed to supplement FM I. In 2005, the German Contact Dermatitis Research Group (DKG) added FM II to their baseline series. /The objective was/ to evaluate reactions to FM II and its constituents in routine patch testing. Retrospective data analysis of the Information Network of Departments of Dermatology (IVDK), 2005-2008, of patch test results with FM II and its constituents. A total of 35,633 patients were patch tested with FM II as part of the DKG baseline series. Of these, 1742 (4.9%) reacted positively. Concomitant reactions to FM I were observed in 41.9% of the patients reacting to FM II. In 367 FM II-positive patients, a full breakdown test of the mix was performed. Of these, 47.7% reacted to hydroxyisohexyl 3-cyclohexene carboxaldehyde, 16.1% to citral, 11.4% to farnesol, 3.8% to hexyl cinnamal, 2.7% to coumarin, and 2.5% to citronellol. FM II is an important screening and diagnostic tool to detect fragrance allergy. Hydroxyisohexyl 3-cyclohexene carboxaldehyde is the most important fragrance allergen in FM II.

/HUMAN EXPOSURE STUDIES/ Fragrance mix II (FM II) was initiated to detect contact hypersenstitivity (CH) to fragrances that could not have been identified previously. OBJECTIVE: The aim of this multicenter study was to map the frequency of CH to FM II and its components in Hungary. METHODS: Six centers participated in the survey from 2009 to 2010. A total off 565 patients (434 women and 131 men) with former skin symptoms provoked by scented products were patch tested. The tests were performed with Brial GmbH D-Greven allergens. In the environmental patch test series, FM II, FM I, Myroxylon pereirae, colophonium, wood-tar mix, propolis, and sesquiterpene lactone mix were tested as fragrance allergens. The FM II components (citral, farnesol, coumarin, citronellol, alpha-hexyl-cinnamaldehyde, and hydroxy-isohexyl-3-cyclohexene-carboxaldehyde [Lyral]) were also tested. RESULTS: Contact hypersenstitivity to any fragrances was detected in 28.8%, to FM II in 17.2% of the patients. Contact hypersenstitivity to hydroxy-isohexyl-3-cyclohexene-carboxaldehyde was observed in 7.3%, to coumarin in 5.1%, to alpha-hexyl-cinnamaldehyde in 3.5%, to citral in 3.4%, to farnesol in 2.5%, and to citronellol in 1.2%. Of the FM II-positive cases, 48.4% showed isolated CH reaction. CONCLUSIONS: The frequency of CH to FM II is 17.2% in the tested, selected Hungarian population. The CH to FM II and its components could not have been revealed without the present test materials.

/HUMAN EXPOSURE STUDIES/ A 24-hr patch test using full strength citronellol produced no irritation reactions in 20 subjects.

/HUMAN EXPOSURE STUDIES/ A maximization test was carried out on 25 volunteers. The material was tested at a concentration of 6% in petrolatum and produced no sensitization reactions.

For more Human Toxicity Excerpts (Complete) data for Citronellol (6 total), please visit the HSDB record page.

Citronellol is a food additive permitted for direct addition to food for human consumption as a synthetic flavoring substance and adjuvant in accordance with the following conditions: a) they are used in the minimum quantity required to produce their intended effect, and otherwise in accordance with all the principles of good manufacturing practice, and b) they consist of one or more of the following, used alone or in combination with flavoring substances and adjuvants generally recognized as safe in food, prior-sanctioned for such use, or regulated by an appropriate section in this part.

Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. (a) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils. Citronellol is included on this list. Limit: When ready for use, the end-use concentration is not to exceed 100 ppm.

An exemption from the requirement of a tolerance is established for residues of the biochemical pesticide citronellol in or on all food commodities.

We evaluated the effects of rose oil on the peroxisome proliferator-activated receptor (PPAR) and cyclooxygenase-2 (COX-2).Citronellol and geraniol, the major components of rose oil, activated PPAR alpha and gamma, and suppressed LPS-induced COX-2 expression in cell culture assays, although the PPARgamma-dependent suppression of COX-2 promoter activity was evident only with citronellol, indicating that citronellol and geraniol were the active components of rose oil.

l-Form: in rose and geranium oils; d-Form: in Ceylon and Java citronella oils; Used in perfumery; [Merck Index] Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Present in over 30 essential oils, fruits, edible plants, wine, beer, and black tea; Active ingredient in pesticide used to control mites on agricultural crops, ornamentals, and landscapes; Also extensively used as fragrance (detergents, soaps, lotions, perfumes, etc.), as a flavoring agent, and component of citronella oil (used in candles, sprays, oils, and insect repellents); [EPA BRADs]

Farming (Pesticides) [Category: Industry]

For citronellol (USEPA/OPP Pesticide Code: 167004) ACTIVE products with label matches. /SRP: Registered for use in the USA but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

Reported uses (ppm):

In perfumery

Citronellol is one of the components responsible for the insect repellent properties of citronella oil ... Citronellol finds extensive use in floral fragrances and in flavors for citrus and other fruit notes. Its stability makes it particularly useful in fragrances for soaps, detergents, and other household products. Citronellol is also important as an intermediate in the synthesis of a number of other aroma chemicals ... Citronellol is the key feedstock for the synthesis of rose oxide.

2023: 10,000,000 - <25,000,000 lb

6-Octen-1-ol, 3,7-dimethyl- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438).

Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: 6-Octen-1-ol, 3,7-dimethyl-. National Production Volume: 4,727,405 lb/yr.

Citronellol

106-22-9:; 3,7-Dimethyl-6-octen-1-ol; 6-Octen-1-ol, 3,7-dimethyl-; Citronellol; dl-Citronellol; Rhodinol pure (commercial name); 1117-61-9:; 3,7-Dimethyloct-6-en-1-ol; 6-Octen-1-ol, 3,7-dimethyl-, (R)-; (R)-3,7-Dimethyloct-6-en-1-ol; (+)-ß-Citronellol; (+)-(R)-Citronellol; 26489-01-0:; 6-Octen-1-ol, 3,7-dimethyl-,(+/-)-; 6812-78-8:; 3,7-Dimethyloct-7-en-1-ol; 7-Octen-1-ol, 3,7-dimethyl-,(S)-; 3,7-Dimethyl-(6-or 7-)octen-1-ol; 3,7-Dimethyl-7-octen-1-ol; 141-25-3:; 3,7-Dimethyloct-7-en-1-ol; 7-Octen-1-ol, 3,7-dimethyl- (isomer unspecified); α-Citronellol; Rhodinol (commercial name); 7540-51-4:; 3,7-Dimethyloct-6-en-1-ol; (-)-3,7-Dimethyloct-6-en-1-ol; (S)-3,7-Dimethyl-6-octen-1-ol; 6-Octen-1-ol, 3,7-dimethyl-, (S)-; l-Citronellol

IFRA_STD_022.pdf

49

IFRA 51st Amendment - Guidance for the use of IFRA Standards

Restriction: This material should be used only in the limited quantity as stated in the Standard

Citronellol is manufactured on a commercial scale by the hydrogenation of nerol and geraniol, which in turn are made either from alpha- or beta-pinene. Hydrogenation of nerol and geraniol over a copper chromite catalyst gives a high yield of citronellol. Fractional distillation of the crude product produces a perfumery-quality citronellol. Geraniol can also be hydrogenated selectively to citronellol, without forming tetrahydrogeraniol, through use of a Raney cobalt catalyst. However, partial hydrogenation using a nickel catalyst does give some tetrahydrogeraniol. The product contains nerol, geraniol, and tetrahydrogeraniol and has odor properties closer to materials derived from citronella oil, and is therefore useful as a perfumery material.

Manufacturing: Woroch et al.; Bain; Webb, United States of America patent 2990422; United States of America patent 3005845; United States of America patent 3028431 (1961, 1961, 1962, all to Glidden); Eschinasi, United States of America patent 30527301962 to Givaudan).

Citronellol may be obtained by reduction of citronellal or geraniol, or by fractional distillation of geranium oil or citronella oil. It may also be prepared synthetically.

Cosmetics product ingredient: Citronellol /+- 3,7-dimethyloct-6-en-1-ol (CITRONELLOL; (3R)-3,7-dimethyloct-6-en-1-ol; (3S)-3,7-dimethyloct-6-en-1-ol)

Information on 643 consumer products that contain Citronellol in the following categories is provided:

Fragrance Ingredients

Fragrance Ingredients

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index

Cosmetics -> Masking

Not Known or Reasonably Ascertainable

6-Octen-1-ol, 3,7-dimethyl-: ACTIVE

2.2 [Products applied to the lips]

0.67 [Products applied to the axillae]

13 [Products applied to the face/body using fingertips]

12 [Products related to fine fragrances]

3.2 [Products applied to the body using the hands (palms), primarily leave-on (Body lotion)]

3.2 [Products applied to the face using the hands (palms), primarily leave-on (Face moisturizer)]