기본 정보
- 표준 SMILES
O=C([O-])CCC(=O)[O-].[Na+].[Na+]- InChIKey
ZDQYSKICYIVCPN-UHFFFAOYSA-L- 분자식
- Na2.C4.H4.O4
- 평균 분자량
- 162.05 g/mol
- 단동위원소 질량
- 161.99049717
개요
Sodium succinate (anhydrous) is an organic sodium salt that is the disodium salt of succinic acid. The hexahydrate form is used as an ingredient of topical preparations for the treatment of cataract. It contains a succinate(2-).
이름 및 식별자
- 우선 이름
- Sodium Succinate
- IUPAC
- disodium;butanedioate
이름 및 동의어
SODIUM SUCCINATEDisodium butanedioatesuccinate sodiumButanedioic acid disodium saltSodium succinate anhydrousV8ZGC8ISR3Sodium succinate, anhydrousCHEBI:63675SODIUM SUCCINATE (MART.)SODIUM SUCCINATE [MART.]ANHYDROUS SODIUM SUCCINATE (USP-RS)ANHYDROUS SODIUM SUCCINATE [USP-RS]
이름 더 보기
RefChem:58243Disodium succinate150-90-3Butanedioic acid, disodium saltSuccinic acid disodium saltJantaran sodnydisodium;butanedioateC4H4Na2O4
데이터베이스 식별자
- CAS
150-90-3、6106-21-4- PubChem CID
- 9020
- DTXSID
DTXSID5059741- ChEMBL
CHEMBL1200345、CHEMBL3907604- ChEBI
CHEBI:63675- UNII
- V8ZGC8ISR3
- EC Number
- 205-778-7
- Nikkaji
- J2.965C
물성
구조 계산 물성
- 극성 표면적
- 80.3 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 4
- 회전 가능 결합 수
- 1
- 무거운 원자 수
- 10
- 형식 전하
- 0
- 복잡도
- 81.6
실험 및 물리화학적 성질
Chemical ClassesMetals -> Organic Acids, Metal Salts
Cosmetics
Cosmetic ingredients (Disodium Succinate) -> CIR (Cosmetic Ingredient Review)
Cosmetic ingredients (Sodium Succinate) -> CIR (Cosmetic Ingredient Review)
Buffering; Surfactant
FragrancesFragrance Ingredient (Disodium succinate) -> IFRA transparency List
Food AdditivesFLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Flavoring AgentsEU Flavoring substances
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physical DescriptionWhite solid; [OECD SIDS: Disodium Succinate - 2003]
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 83.9% (230 of 274) of all reports.
Warning
H315 (16.1%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 274 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Regulatory Information
Chemical: Butanedioic acid, disodium salt
Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)
Status: Active Update: 13-12-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/17733
Butanedioic acid, disodium salt: Does not have an individual approval but may be used under an appropriate group standard
Sodium succinate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Butanedioic acid, disodium salt: Human health tier I assessment
Hazards Summary
Effects suggestive of kidney toxicity observed in repeated-dose oral study of rats; No evidence of reproductive or developmental toxicity in rats at doses up to 1,000 mg/kg/day; [OECD SIDS: Disodium Succinate - 2003] Safe when used as a flavoring agent in food; [EFSA] A skin and strong eye irritant; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (16.1%)
안전 및 보호
Protective Action Criteria (PAC)
15 [mg/m3]
160 [mg/m3]
970 [mg/m3]
독성 정보
Toxicity Summary
Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
화학 및 산업
용도 및 제조
Uses
CIR ingredient: Disodium Succinate
CIR ingredient: Sodium Succinate
Used as an acidulant and flavoring agent for foods and as a protective coating for fruits and vegetables; [Merck Index] A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851) [ChemIDplus] Used as a flavoring agent; [FDA]
Use Classification
Fragrance Ingredients
Cosmetics -> Buffering; Surfactant
General Manufacturing InformationButanedioic acid, sodium salt (1:2): ACTIVE
관련 반응
10건
연결된 노트
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