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플로로페놀

2-Fluorophenol

HCID 9707
새 노트새 반응견적 요청하기
인쇄 미리보기

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기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
367-12-4
표준 SMILES
Oc1ccccc1F
InChIKey
HFHFGHLXUCOHLN-UHFFFAOYSA-N
분자식
C6H5FO
평균 분자량
112.1 g/mol
단동위원소 질량
112.032443

개요

2-fluorophenol appears as liquid or crystalline solid melting at 14-16 °C. Corrosive. Density 1.246 g / cm3.

이름 및 식별자

우선 이름
2-Fluorophenol
IUPAC
2-fluorophenol
현지명
플로로페놀
영어명
2-Fluorophenol
분자식
C6H5FO
분자량
112.1

이름 및 동의어

2-FLUOROPHENOL367-12-4o-FluorophenolPhenol, 2-fluoro-1-Fluoro-2-hydroxybenzenePhenol, o-fluoro-DTXSID0047745I9OW1NLY9RNSC-10294DTXCID0027729RefChem:472648206-681-2
이름 더 보기
플로로페놀2-플루오로페놀1-Bromo-3-fluorobezeneuorophenoL2-Florophenol2-Flurophenolo-fluoro-pheno2-fluoro-pheno2-Fluorophenole2-Fluorophenol f
Fluorophenol2-fluoro-phenolMFCD000021552-fluorohydroxybenzenePhenol, fluoro-CCRIS 1226EINECS 206-681-2UNII-I9OW1NLY9R

데이터베이스 식별자

CAS
367-12-4
PubChem CID
9707
DTXSID
DTXSID0047745
ChEMBL
CHEMBL224144
UNII
I9OW1NLY9R
EC Number
206-681-2
Nikkaji
J110.443H

물성

구조 계산 물성보충 중

XLogP
1.7
극성 표면적
20.2 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
2
회전 가능 결합 수
0
무거운 원자 수
8
형식 전하
0
복잡도
74.9

실험 및 물리화학적 성질

Chemical ClassesOther Classes -> Phenols
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
LogP1.71
Boiling Point304 to 306 °F at 760 mmHg (NTP, 1992)
Melting Point61 °F (NTP, 1992)
Vapor Pressure1.19 [mmHg]
Physical Description · 2건

2-fluorophenol appears as liquid or crystalline solid melting at 14-16 °C. Corrosive. Density 1.246 g / cm3.

Liquid or solid; mp = 14-16 deg C; [CAMEO] Colorless liquid; [MSDSonline]

물리화학적 성질

녹는점
16.1 °C · 16.1 °C (lit.)
끓는 점
171 · 171-172 °C/741 mmHg (lit.)
밀도
1.256 g/mL · 1.256 g/mL at 25 °C (lit.)
굴절률
20 · n20/D 1.511(lit.)
인화점

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 3.3% (1 of 30) of reports.

Danger

H226 (96.7%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 30 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Chemical: Phenol, 2-fluoro-

2-Fluorophenol: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelCombustible Liquid
Fire HazardsExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Health HazardsACUTE/CHRONIC HAZARDS: Toxic and irritant. (NTP, 1992)
Hazards SummaryAn irritant; [CAMEO] A skin and eye irritant; [eChemPortal: ERMA] An irritant; [MSDSonline]
Reactive GroupPhenols and Cresols
Reactivity AlertsHighly Flammable
Reactivity Profile · 1건

2-FLUOROPHENOL reacts as a weak organic acid. May be incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction with bases. Such heating may initiate polymerization of the organic compound. Sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Nitrated very rapidly, even by dilute nitric acid.

화학 및 산업

용도 및 제조

General Manufacturing InformationPhenol, 2-fluoro-: ACTIVE

응용 분야

일반 설명Liquid or crystalline solid melting at 14-16°C. Corrosive. Density 1.246 g / cm3.

상·하류 제품 정보

상류 원료

O-클로로니트로벤젠플루오르화칼륨수소1-아세톡시-2-플루오로벤젠3'-플루오로-4'-하이드록시아세토페논

하류 제품

3-플루오로-4-히드록시벤즈알데히드1,4-벤조디옥산4-브로모-2-플루오로-3-메톡시-벤조익산4-브로모-2-플로로펜올3"-플루오로-2"-하이드록시아세토페논2-플루오로-3-하이드록시벤잘데하이드

관련 반응

266건
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화합물 노트

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이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
더보기
새 노트새 반응견적 요청하기
116 °F · 116 °F
저장 조건
Inert atmosphere,Room Temperature
용해도
37.7 g/L · 37.7g/L
물리적 상태
액체
산도 계수 (pKa)
8.73 · 8.73(at 25℃)
Specific Gravity
1.256 · 1.256
색상
투명한 무색~연한 황갈색을 띤다.
수용성
80.72 g/L · 80.72g/L(25℃)
BRN
1905112 · 1905112
Henry's Law Constant
3.1 · 3.1×100 mol/(m3Pa) at 25℃, Abraham et al. (1994)
안정성
안정적인. 가연성. 강한 산화제와 호환되지 않습니다.
InChI
1S/C6H5FO/c7-5-3-1-2-4-6(5)8/h1-4,8H
InChIKey
HFHFGHLXUCOHLN-UHFFFAOYSA-N
SMILES
Oc1ccccc1F
NIST
2 · Phenol, 2-fluoro-(367-12-4)
EPA
o-Fluorophenol (367-12-4)

화학적 성질

Clear colourless to yellow liquid

Air and Water ReactionsHighly flammable.
Hazard Classes and CategoriesFlam. Liq. 3 (96.7%)

안전 및 보호

Fire Fighting · 1건

This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. (NTP, 1992)

First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

독성 정보

EPA Provisional Peer-Reviewed Toxicity Values · 3건

2-Fluorophenol

PDF Document

2004

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
SL4530000
ridadr
UN 1993 3/PG 3
HS 번호
29081000
risk_code
20/21/22-36/37/38-10-63-43-23/24/25-45-40
hazard_code
Xn,F,C,Xi,T
safety_code
28-36/37-36/37/39-26-16-24/25-23-53-36
포장분류
III
위험 등급
3
위험 참고 사항
Flammable/Corrosive
Hazard Classifications
Acute Tox. 4 DermalAcute Tox. 4 InhalationAcute Tox. 4 OralAquatic Chronic 3Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2
스토리지 클래스
3 - Flammable liquids
3-FLUORO-2-METHOXYBENZALDEHYDE
2-Bromo-6-fluorophenol
2-플루오로-6-니트로페놀
2,4,5-트리클로로벤조산