2,4-디플루오로아닐린

2,4-Difluoroaniline

HCID 9709CAS 367-25-9

기본 정보

표준 SMILES
Nc1ccc(F)cc1F
InChIKey
CEPCPXLLFXPZGW-UHFFFAOYSA-N
분자식
C6H5F2N
평균 분자량
129.11 g/mol
단동위원소 질량
129.0390056

개요

2,4-difluoroaniline is a dark reddish-purple liquid. (NTP, 1992)

이름 및 식별자

우선 이름
2,4-Difluoroaniline
IUPAC
2,4-difluoroaniline
현지명
2,4-디플루오로아닐린
영어명
2,4-Difluoroaniline
분자식
C6H5F2N
분자량
129.11

이름 및 동의어

2,4-DIFLUOROANILINE367-25-92,4-DifluorobenzenamineBenzenamine, 2,4-difluoro-Aniline, 2,4-difluoro-DTXSID602506440P93L7KWDNSC-10297DTXCID905064RefChem:82418206-687-52,4-Difluroaniline
이름 더 보기
2,4-디플루오로아닐린2,4-다이플루오로아닐린Difluoroaniline4-Difluoroaniline2,4-difluoro-anilinAKOS 911272,4-Difluoranilin2,4-DIFLOUROANILINE
2,4-DifluorophenylamineMFCD000076482.4-difluoroaniline2,?4-?difluoro-BenzenamineFlurbiprofen Impurity 53CCRIS 46212,4-Difluoro AnilineEINECS 206-687-5

데이터베이스 식별자

CAS
367-25-9
PubChem CID
9709
DTXSID
DTXSID6025064
ChEMBL
CHEMBL1423658
UNII
40P93L7KWD
EC Number
206-687-5
Nikkaji
J193.875D

물성

구조 계산 물성

XLogP
1.5
극성 표면적
26 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
0
무거운 원자 수
9

실험 및 물리화학적 성질

Density1.268 (NTP, 1992) - Denser than water; will sink
Solubility10 to 50 mg/mL at 68.9 °F (NTP, 1992)
Flash Point145 °F (NTP, 1992)
Boiling Point338 °F at 753 mmHg (NTP, 1992)
Melting Point18.5 °F (NTP, 1992)
Physical Description2,4-difluoroaniline is a dark reddish-purple liquid. (NTP, 1992)

물리화학적 성질

녹는점
-7.5 °C · -7.5 °C (lit.)
끓는 점
170 °C/753 · 170 °C/753 mmHg (lit.)
밀도
1.268 g/mL · 1.268 g/mL at 25 °C (lit.)
굴절률
20 · n20/D 1.506(lit.)
인화점
145 °F · 145 °F
저장 조건
2 · Keep in dark place,Inert atmosphere,2-8°C

화학적 성질

dark red liquid

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H302 (99.4%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 157 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 3건

Chemical: Benzenamine, 2,4-difluoro-

Status: Active Update: 19-02-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/24338

Benzenamine, 2,4-difluoro-: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelPoison
Fire HazardsThis compound is combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: This compound may be irritating to tissues. (NTP, 1992)
Reactive GroupAryl Halides
Reactivity Profile · 1건

Anilines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

안전 및 보호

Fire FightingFires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
BX3680000
ridadr
UN 2941 6.1/PG 3
HS 번호
29214210
risk_code
20/21/22-36/37/38

화학 및 산업

용도 및 제조

General Manufacturing InformationBenzenamine, 2,4-difluoro-: ACTIVE

응용 분야

용도2,4-Difluoroaniline is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

일반 설명Dark reddish-purple liquid.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
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上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

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