N-에틸리도카인브로마이드

QX-314 bromide

HCID 9884487

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 24003-58-5
표준 SMILES: CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C.[Br-]
InChIKey: DLHMKHREUTXMCH-UHFFFAOYSA-N
분자식: C16H27BrN2O
평균 분자량: 343.3 g/mol
단동위원소 질량: 342.13067558

개요

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이름 및 식별자

우선 이름: QX-314 bromide
IUPAC: [2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium bromide
현지명: N-에틸리도카인브로마이드
영어명: N-ETHYLLIDOCAINE BROMIDE
분자식: C16H27BrN2O
분자량: 343.31

이름 및 동의어

24003-58-5N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromideQX-314 BROMIDE3OYF1S84ENDTXSID001018052Ethanaminium, 2-((2,6-dimethylphenyl)amino)-N,N,N-triethyl-2-oxo-, bromide (1:1)Ethanaminium, 2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxo-, bromide (1:1)RefChem:178403DTXCID401476274Lidocaine N-ethyl bromideQX 314 bromideQX-314 (bromide)

이름 더 보기

N-에틸리도카인브로마이드N-ETHYLLIDOCAINE BROMIDEQX 314 bromide,QX314 bromide[2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium:bromide2-[(2,6-DIMETHYLPHENYL)AMINO]-N,N,N-TRIETHYL-2-OXO-ETHANAMINIUM BROMIDE

Lidocaine N-ethyl bromide quaternary salt[2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium;bromideUNII-3OYF1S84ENMFCD00083182QX-314 BrSR-01000075323QX314 BromideMLS000859919

데이터베이스 식별자

CAS: 24003-58-5
PubChem CID: 9884487
DTXSID: DTXSID001018052
ChEMBL: CHEMBL1255750
UNII: 3OYF1S84EN

물성

구조 계산 물성

극성 표면적: 29.1 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 6
무거운 원자 수: 20
형식 전하: 0
복잡도: 268

실험 및 물리화학적 성질

Solubility>51.5 [ug/mL] (The mean of the results at pH 7.4)

물리화학적 성질

녹는점: 214 · 214-215 °C
저장 조건: Desiccate at RT
용해도: 10.5 mg/mL · insoluble in EtOH; ≥10.5 mg/mL in H2O; ≥25.55 mg/mL in DMSO
물리적 상태: 결정질 고체
색상: 하얀색
수용성: 100 mM까지 · 물에 100mM까지 용해됨

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 1건

Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.

응용 분야

용도QX-314 bromide is a derivative of Lidocaine. It is a local anesthetic.

상·하류 제품 정보

상류 원료

리도카인 에틸브로마이드

공급사32 곳

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