DL-3-페닐알라닌

Dl-Phenylalanine

HCID 994CAS 150-30-1

기본 정보

표준 SMILES
NC(Cc1ccccc1)C(=O)O
InChIKey
COLNVLDHVKWLRT-UHFFFAOYSA-N
분자식
C9H11NO2
평균 분자량
165.19 g/mol
단동위원소 질량
165.07897859

개요

Phenylalanine is an aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group. It has a role as a Daphnia magna metabolite. It is an alpha-amino acid and an aromatic amino acid. It contains a benzyl group. It is a conjugate base of a phenylalaninium. It is a conjugate acid of a phenylalaninate.

이름 및 식별자

우선 이름
Dl-Phenylalanine
IUPAC
2-amino-3-phenylpropanoic acid
현지명
DL-3-페닐알라닌
영어명
DL-Phenylalanine
분자식
C9H11NO2
분자량
165.19

이름 및 동의어

DL-PHENYLALANINE150-30-1DL-3-PhenylalaninePhenylalanine DL-formPhenylalanine, dl-DL-2-Amino-3-phenylpropanoic acidFEMA No. 3726NSC 9959DTXSID9023463d,l-phenylalanineEINECS 205-756-7CCRIS 8601
이름 더 보기
DL-3-페닐알라닌3-AMINO-3-PHENYLPROPANOIC ACIDH-DL-PHE-OHDL-PHENYALANINE3 AMINO-PHENYLPROPIONIC ACIDD,L-PHEDLPA 375FEMA 3726DL-Phenylalani
AI3-18436PHENYLALANINE DL8P946UF12SNSC-9959DL-PHENYLALANINE [FCC]DTXCID103463DL-PHENYLALANINE [FHFI]DL-PHENYLALANINE [WHO-DD]

데이터베이스 식별자

CAS
150-30-1、30394-07-1、63-91-2、673-06-3
PubChem CID
994
DTXSID
DTXSID9023463
ChEMBL
CHEMBL25080
ChEBI
CHEBI:28044
UNII
8P946UF12S
EC Number
205-756-7
Nikkaji
J1.258K

물성

구조 계산 물성

XLogP
-1.5
극성 표면적
63.3 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
3
회전 가능 결합 수
3
무거운 원자 수
12

실험 및 물리화학적 성질

Chemical ClassesBiological Agents -> Amino Acids and Derivatives
DrugsPharmaceuticals
Food AdditivesFLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Flavoring AgentsEU Flavoring substances
Solubility · 2건

Soluble in water and dilute mineral acid and alkali hydroxide solutions

Slightly soluble (in ethanol)

Vapor Pressure0.00000005 [mmHg]

물리화학적 성질

녹는점
266 · 266-267 °C (dec.) (lit.)
끓는 점
293.03 °C · 293.03°C (rough estimate)
밀도
1.1603 · 1.1603 (rough estimate)
굴절률
1.52 · 1.5200 (estimate)
FEMA
3726 · 3726 | D,L-PHENYLALANINE
저장 조건
Store at RT.

화학적 성질

DL-Phenylalanine has a sweet taste. It is an essential amino acid that plays a key role in the biosynthesis of other amino acids and some neurotransmitters.

안전 및 규제

GHS 분류

GHS Classification · 3건

This chemical does not meet GHS hazard criteria for 99.1% (112 of 113) of all reports.

Not Classified

Aggregated GHS information provided per 113 reports by companies from 2 notifications to the ECHA C&L Inventory.

유해성 정보

Regulatory Information · 3건

Chemical: DL-Phenylalanine

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Phenylalanine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - DL-Phenylalanine: Human health tier I assessment
Hazards SummarySafe when used as a flavoring agent in food; [EFSA] Not considered hazardous by GHS classification; [Sigma-Aldrich MSDS] See Phenylalanine.
Hazard Classes and CategoriesNot Classified

안전 데이터

wgk
3
tsca
TSCA listed
HS 번호
29224995
risk_code
36/37/38-34
hazard_code
Xi,C
safety_code
37/39-24/25-45-36/37/39-27-26

화학 및 산업

용도 및 제조

UsesUsed as a component of aspartame and as a nutrient; [Merck Index] Used as a flavoring agent; [FDA]
Use Classification · 2건

Flavoring Agents -> JECFA Flavorings Index

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

General Manufacturing InformationPhenylalanine: ACTIVE
응용 분야 · 3건

출처Phenylalanine is the most commonly found aromatic amino acid in proteins and enzymes with a molar ratio of 3.5% compared to the other amino acids, about double the amount of any other aromatic amino acid. Reported found in white bread, macaroni, egg noodles, corn flakes, corn grits, oatmeal, wheat bran, wheat flakes, shredded wheat, barley, brown rice, rye flour, whole grain wheat flour, buttermilk, blue cheese, cheddar cheese, cottage cheese, cream cheese, parmesan cheese, bacon, cured ham, frankfurters, pork sausage, canned red kidney beans, canned sweet corn, canned peas, canned lima beans, canned potatoes, canned asparagus, canned snap beans, canned beets, beef, lamb, fresh ham, veal round, beef liver, chicken, chicken liver, turkey and other natural sources.

용도DL-Phenylalanine is used torelieve cases of minor depressionand other mood issues as well as and physical discomforts and pain. It is also used in acupunctureanesthesia, alcohol withdrawal.

일반 설명Phenylalanine is an amino acid. It participates in the preparation of ternary piroxicam complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II). Characterization of these complexes by elemental analyses, molar conductance, IR, UV-Vis, magnetic moment, diffuse reflectance and X-ray powder diffraction methods has been conducted. Crystalline DL-phenylalanine was prepared by its reduction in silica gel by solubility method.

제조 방법

By microbial bioengineered process.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]
추가 설명 · 4건

순도시험(1) 납 : 이 품목 5.0g을 취하여 원자흡광광도법 또는 유도결합라즈마발광광도법에 따라 시험할 때, 그 양은 5.0ppm 이하이어야 한다.

확인시험(1) 이 품목의 수용액(1→1,000) 5mL에 닌히드린시액 1mL를 가하여 가열하면 자색을 나타낸다. (2) 이 품목의 수용액(1→100) 5mL에 중크롬산칼륨시액 몇 방울을 가하여 가열하면 특유한 냄새가 난다. (3) 이 품목 10mg에 질산칼륨 0.5g 및 황산 2mL를 가하여 수욕상에서 20분간 가열한 다음 식히고 히드록실아민시액 2mL를 가하여 얼음물 중에 10분간 방치한 다음 즉시 수산화나트륨시액 10mL를 가하여 방치하면 자색을 나타낸다.

정량법이 품목을 105℃에서 2시간 미리 건조한 다음 약 0.5g을 정밀히 달아 빙초산(비수적정용) 70mL를 가하여 녹이고 0.1N 과염소산용액으로 적정한다(지시약 : 크리스탈바이올렛․빙초산시액 2방울). 종말점은 액의 자색이 청색을 지나 녹색으로 변하는 점이다. 따로 같은 방법으로 공시험을 한다.0.1N 과염소산용액 1mL = 16.52mg C9H11NO2

정의ChEBI: An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.

관련 반응

140건

연결된 노트

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