Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Carbamate → 5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-ylmethyl palmitoylcarbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Carbamate | HCID 276 | — |
| 반응물 | (5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-yl)methanol | HCID 473933 | — |
| 반응물 | Palmitoyl isocyanate | HCID 18792000 | — |
| 생성물 | 5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-ylmethyl palmitoylcarbamate | HCID 69686480 | 57% |
반응 단계
The compound 19 (250 mg, 0.725 mmol) was converted to the carbamate with palmitoyl isocyanate (5 eq.) in the same manner as the example 66 to give the compound 85 (259 mg, 57%). Mp. 95-97° C. Rf 0.33 (1:2 EtOAc - hexane).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06054591 |
| 출처 데이터셋 | uspto-grants-2000_04 |
| ORD ID | ord-5d912f3f93464a7dbab55e98775b76b9 |
| 출처 메모 | uspto-grants-2000_04 |