2-(1-Methyl-1H-imidazol-4-yl)ethanamine bis(4-methylbenzenesulfonate) → 1-Methylhistamine

HRID 1014963

반응식

HRID 1014963 반응식
CC1C=CC(S(O)(=O)=O)=CC=1.CC1C=CC(S(O)(=O)=O)=CC=1.[CH3:23][N:24]1[CH:28]=[C:27]([CH2:29][CH2:30][NH2:31])[N:26]=[CH:25]1>O>[CH3:23][N:24]1[CH:28]=[C:27]([CH2:29][CH2:30][NH2:31])[N:26]=[CH:25]1

참가 물질

3

반응물 1

HCID 862548242-(1-Methyl-1H-imidazol-4-yl)ethanamine bis(4-methylbenzenesulfonate)

생성물 1

HCID 36141-Methylhistamine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

[2-(1-methyl-1H-imidazol-4-yl)ethyl]amine bis(4-methylbenzenesulfonate) (50 g) was dissolved in IMS (200 ml)/water (200 ml). This was passed through a DOWEX550A column (600 g), eluting with IMS (ca. 4 litres). Appropriate fractions were combined and concentrated in vacuo to yield the title compound, 13.4 g.

후처리

  1. washeluting with IMS (ca. 4 litres)
  2. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-f3da4045887c466dbdc32a66a7e10fda
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07985740B2

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