Hydrochloric Acid → 3-Amino-2-(thiophen-3-yl)propanoic acid
반응식
O=C1C2C(=CC=CC=2)C(=O)[N:3]1[CH2:12][CH:13]([C:18]1[CH:22]=[CH:21][S:20][CH:19]=1)[C:14]([O:16]C)=[O:15].Cl>>[NH2:3][CH2:12][CH:13]([C:18]1[CH:22]=[CH:21][S:20][CH:19]=1)[C:14]([OH:16])=[O:15]참가 물질
3
실험 절차
To methyl 3-(1,3-dioxoisoindolin-2-yl)-2-(thiophen-3-yl)propanoate (E429) was added 6 N HCl and the solution was refluxed for 4 h. The solvents were evaporated to give 3-amino-2-(thiophen-3-yl)propanoic acid (E430).
후처리
- temperaturethe solution was refluxed for 4 h
- customThe solvents were evaporated
출처 및 근거
- ORD 기록
- ord-1adcd1f7fd1c4a55bb28d3ade82fe2d5
- 출처 데이터셋
- uspto-grants-2014_05
- 특허 번호
- US08716310B2
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