Potassium Carbonate → 2-(5-Fluoro-2-(hydroxymethyl)-3-(3-methyl-7-(5-(4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-ylamino)-3H-benzo[d]imidazol-5-yl)phenyl)-3,4,6,7,8,9-hexahydropyrazino[1,2-a]indol-1(2H)-one

반응식

Cl[C:2]1[CH:3]=[C:4]([NH:12][C:13]2[CH:18]=[CH:17][C:16]([N:19]3[CH2:24][CH2:23][N:22]([CH:25]4[CH2:28][O:27][CH2:26]4)[CH2:21][CH2:20]3)=[CH:15][N:14]=2)[C:5]2[N:9]=[CH:8][N:7]([CH3:10])[C:6]=2[CH:11]=1.C([O:32][CH2:33][C:34]1[C:39](B2OC(C)(C)C(C)(C)O2)=[CH:38][C:37]([F:49])=[CH:36][C:35]=1[N:50]1[CH2:62][CH2:61][N:53]2[C:54]3[CH2:55][CH2:56][CH2:57][CH2:58][C:59]=3[CH:60]=[C:52]2[C:51]1=[O:63])(=O)C.C(=O)([O-])[O-].[K+].[K+].C1(P(C2CCCCC2)C2CCCCC2)CCCCC1>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[F:49][C:37]1[CH:38]=[C:39]([C:2]2[CH:3]=[C:4]([NH:12][C:13]3[CH:18]=[CH:17][C:16]([N:19]4[CH2:20][CH2:21][N:22]([CH:25]5[CH2:26][O:27][CH2:28]5)[CH2:23][CH2:24]4)=[CH:15][N:14]=3)[C:5]3[N:9]=[CH:8][N:7]([CH3:10])[C:6]=3[CH:11]=2)[C:34]([CH2:33][OH:32])=[C:35]([N:50]2[CH2:62][CH2:61][N:53]3[C:54]4[CH2:55][CH2:56][CH2:57][CH2:58][C:59]=4[CH:60]=[C:52]3[C:51]2=[O:63])[CH:36]=1