4-Methylmorpholine → tert-Butyl (2-{4-[({2-[(2,3-difluorobenzyl)thio]-6-methoxypyrimidin-4-yl}amino)sulfonyl]piperazin-1-yl}-2-oxoethyl)carbamate

반응식

[C:1]([O:5][C:6]([NH:8][CH2:9][C:10]([OH:12])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].C1(N=C=NC2CCCCC2)CCCCC1.O.ON1C2C=CC=CC=2N=N1.Cl.[F:40][C:41]1[C:46]([F:47])=[CH:45][CH:44]=[CH:43][C:42]=1[CH2:48][S:49][C:50]1[N:55]=[C:54]([NH:56][S:57]([N:60]2[CH2:65][CH2:64][NH:63][CH2:62][CH2:61]2)(=[O:59])=[O:58])[CH:53]=[C:52]([O:66][CH3:67])[N:51]=1.CN1CCOCC1>CN(C=O)C>[F:40][C:41]1[C:46]([F:47])=[CH:45][CH:44]=[CH:43][C:42]=1[CH2:48][S:49][C:50]1[N:55]=[C:54]([NH:56][S:57]([N:60]2[CH2:61][CH2:62][N:63]([C:10](=[O:12])[CH2:9][NH:8][C:6](=[O:7])[O:5][C:1]([CH3:2])([CH3:3])[CH3:4])[CH2:64][CH2:65]2)(=[O:58])=[O:59])[CH:53]=[C:52]([O:66][CH3:67])[N:51]=1