Potassium Carbonate → HCID 58079363, 화합물

HRID 1027368노트

반응식

HRID 1027368 반응식
C[O:2][C:3]1[CH2:8][C:7]([O:9]C)=[CH:6][CH:5]([CH2:11][CH:12]2[O:16][CH2:15][CH2:14][O:13]2)[CH:4]=1.C(=O)([O-])[O-].[K+].[K+]>Cl.O1CCCC1>[O:13]1[CH2:14][CH2:15][O:16][CH:12]1[CH2:11][CH:5]1[CH2:6][C:7](=[O:9])[CH2:8][C:3](=[O:2])[CH2:4]1

참가 물질

5

반응물 2

HCID 11430Potassium CarbonateHCID 58079340HCID 58079340, 화합물

생성물 1

HCID 58079363HCID 58079363, 화합물

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 8028Tetrahydrofuran용매

실험 절차

A solution of 2-(3,5-dimethoxycyclohexa-2,5-dienylmethyl)-[1,3]-dioxolane (730 mgs, 3.2 mmol) in a mixture of 10% aqueous hydrochloric acid (2.9 ml) and tetrahydrofuran (29 ml) is stirred at room temperature for ¾ hour. The reaction mixture is poured into an aqueous solution of saturated potassium carbonate and extracted with ethyl acetate. The organic extract is discarded. The aqueous extract is acidified with dilute aqueous hydrochloric acid and extracted with ethyl acetate. The organic extract is dried over anhydrous magnesium sulfate, filtered and then filtrate evaporated in vacuo to give 5-([1,3]-dioxolan-2-ylmethyl)-cyclohexane-1,3-dione as a white solid, used without further purification in the next step.

후처리

  1. extractionextracted with ethyl acetate
  2. extractionThe organic extract
  3. extractionThe aqueous extract
  4. extractionextracted with ethyl acetate
  5. extractionThe organic extract
  6. dry with materialis dried over anhydrous magnesium sulfate
  7. filtrationfiltered
  8. customfiltrate evaporated in vacuo

출처 및 근거

ORD 기록
ord-9a346089337244ef946783237a28a2a8
출처 데이터셋
uspto-grants-2014_05
특허 번호
US08735322B2

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