Acrylic Acid → Oxan-2-yl prop-2-enoate

HRID 1029349

반응식

HRID 1029349 반응식
[C:1]([OH:5])(=[O:4])[CH:2]=[CH2:3].[O:6]1[CH:11]=[CH:10][CH2:9][CH2:8][CH2:7]1>ClCCl>[C:1]([O:5][CH:7]1[CH2:8][CH2:9][CH2:10][CH2:11][O:6]1)(=[O:4])[CH:2]=[CH2:3]

참가 물질

4

반응물 2

HCID 6581Acrylic AcidHCID 80803,4-dihydro-2H-pyran

생성물 1

HCID 21909470Oxan-2-yl prop-2-enoate수율 26%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of 10.5 g (146 mmol, 10 ml) acrylic acid and 14.0 g (166 mmol, 15.2 ml) dihydropyran in 40 ml dichloromethane was stirred at room temperature for one day. The mixture was washed with saturated aqueous sodium bicarbonate and the organic layer was concentrated in vacuo. The residue was distilled to give 5.93 g (38.0 mmol, 26% yield) tetrahydropyran-2-yl acrylate, bp 40° C. at 0.2 torr.

후처리

  1. washThe mixture was washed with saturated aqueous sodium bicarbonate
  2. concentrationthe organic layer was concentrated in vacuo
  3. distillationThe residue was distilled

출처 및 근거

ORD 기록
ord-4e009b6f86f44acf8a27f606ca8b642b
출처 데이터셋
uspto-grants-1992_04
특허 번호
US05102771

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