Triethylamine → 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one

HRID 1029355

반응식

HRID 1029355 반응식
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.S(C1C=CC(C)=CC=1)([O-])(=O)=O.CS[C:27]1[S:28][C:29]2[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=2[N+:31]=1[CH3:32].C(N(CC)CC)C>CO>[CH3:32][N:31]1[C:30]2[CH:33]=[CH:34][CH:35]=[CH:36][C:29]=2[S:28](=[C:6]2[C:5](=[O:7])[N:4]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[NH:3][CH:2]2[CH3:1])[CH2:27]1

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 41464Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1)HCID 703351H-Pyrazol-5-ol, 3-methyl-1-phenyl-

생성물 1

HCID 867456114-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.68 g (0.01 mol) 2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for one hour, then filtered and washed with methanol. After drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000).

후처리

  1. filtrationfiltered
  2. washwashed with methanol
  3. customAfter drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000)

출처 및 근거

ORD 기록
ord-6cbb14defca149e0998b6ab85d6dad14
출처 데이터셋
uspto-grants-1992_04
특허 번호
US05102781

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