Sodium Hydroxide → 1-[4-(5-Methyl-3-oxo-2,3,4,5-tetrahydro-6-pyridazinyl)-2-nitro-phenyl]-piperidine-4-carboxylic acid
반응식
C([O:3][C:4]([CH:6]1[CH2:11][CH2:10][N:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]3[CH:19]([CH3:25])[CH2:20][C:21](=[O:24])[NH:22][N:23]=3)=[CH:14][C:13]=2[N+:26]([O-:28])=[O:27])[CH2:8][CH2:7]1)=[O:5])C.[OH-].[Na+]>COC(O)C>[CH3:25][CH:19]1[C:18]([C:15]2[CH:16]=[CH:17][C:12]([N:9]3[CH2:8][CH2:7][CH:6]([C:4]([OH:5])=[O:3])[CH2:11][CH2:10]3)=[C:13]([N+:26]([O-:28])=[O:27])[CH:14]=2)=[N:23][NH:22][C:21](=[O:24])[CH2:20]1참가 물질
4
실험 절차
1.2 g (3.1 mmol) of 1-[2-nitro-4-(5-methyl-3-oxo-2,3,4,5-tetrahydro-6-pyridazinyl)-phenyl]-piperidine-4-carboxylic acid ethyl ester are heated under reflux in a solution of 0.4 g (9.3 mmol) of sodium hydroxide in 40 ml of methoxyethanol.