Methyl iodide → N-benzyl-5,6-dihydroxy-N-methylisoindolinium iodide
반응식
[CH2:1]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][C:12]([OH:18])=[C:13]([OH:17])[CH:14]=2)[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][I:20]>CC(C)=O>[I-:20].[CH2:1]([N+:8]1([CH3:19])[CH2:9][C:10]2[C:15](=[CH:14][C:13]([OH:17])=[C:12]([OH:18])[CH:11]=2)[CH2:16]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
4
실험 절차
590 mg (2.44 mmol) of N-benzyl-5,6-dihydroxyisoindoline was dissolved in 10 ml of acetone, and 0.16 ml (2.5 mmol) of methyl iodide was added thereto at room temperature. The mixture was left to stand for 4 hours, and the precipitated crystals were collected by filtration and washed with 10 ml of acetone to obtain 733 mg of the above identified compound.
후처리
- customat room temperature
- waitThe mixture was left
- filtrationthe precipitated crystals were collected by filtration
- washwashed with 10 ml of acetone
- customto obtain 733 mg of the
출처 및 근거
- ORD 기록
- ord-02273bc8a8ef42859fe8c5c28fb83604
- 출처 데이터셋
- uspto-grants-1990_09
- 특허 번호
- US04958029
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