HCID 54049086, 화합물 → (3-Benzyloxy-4-nitrophenyl)acetonitrile

HRID 1032519

반응식

HRID 1032519 반응식
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:18]=[CH:19][N:20](C)C)[CH:12]=[CH:13][C:14]=1[N+:15]([O-:17])=[O:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>O>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:18][C:19]#[N:20])[CH:12]=[CH:13][C:14]=1[N+:15]([O-:17])=[O:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 1

HCID 54049086HCID 54049086, 화합물

생성물 1

HCID 13629306(3-Benzyloxy-4-nitrophenyl)acetonitrile수율 45.8%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

18.7 g of N-[2-(3-benzyloxy-4-nitrophenyl)ethenyl]-N,N-dimethylamine and 21.3 g of hydroxylamineorthosulfonic acid in 420 ml of water are stirred for 3 days at room temperature. The thus-separated solid product is chromatographed on silica gel with cyclohexane/acetic acid (1:1), thus obtaining 7.7 g of (3-benzyloxy-4-nitrophenyl)acetonitrile, mp 73°-85° C.

후처리

  1. customThe thus-separated solid product is chromatographed on silica gel with cyclohexane/acetic acid (1:1)

출처 및 근거

ORD 기록
ord-22bb6ba83c244b488df30ab3579dde84
출처 데이터셋
uspto-grants-1990_09
특허 번호
US04958026

연결된 노트

불러오는 중…