Propanal → 1-(1-Propenyl)-2-nitroiminoimidazolidine

HRID 1033548노트

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HRID 1033548 반응식
[N+:1]([N:4]=[C:5]1[NH:9][CH2:8][CH2:7][NH:6]1)([O-:3])=[O:2].[CH:10](=O)[CH2:11][CH3:12].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O.O>CN(C)C=O.C(OCC)(=O)C>[CH:10]([N:6]1[CH2:7][CH2:8][NH:9][C:5]1=[N:4][N+:1]([O-:3])=[O:2])=[CH:11][CH3:12]

참가 물질

7

반응물 4

HCID 527PropanalHCID 962WaterHCID 14812Phosphorus oxide (P4O10)HCID 135413413N-nitroimidazolidin-2-imine

생성물 1

HCID 1363783921-(1-Propenyl)-2-nitroiminoimidazolidine수율 65.8%

시약·촉매·용매 2

HCID 6228Dimethylformamide용매HCID 8857Ethyl Acetate용매

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온도
10 °C

실험 절차

5.0 g of 2-nitroiminoimidazolidine and 4.5 g of propionaldehyde were dissolved in 25 ml of N,N-dimethylformamide, and 4.0 g of phosphorus pentoxide was added thereto with cooling with ice over a period of 20 minutes and thereafter stirred for 10 minutes at 10° C. 20 ml of water and 20 ml of ethyl acetate were added to the reaction mixture, and the crystals thus precipitated out were filtrated and dried to give 4.3 g of 1-(1-propenyl)-2-nitroiminoimidazolidine.

후처리

  1. temperaturewith cooling with ice over a period of 20 minutes
  2. customthe crystals thus precipitated out
  3. filtrationwere filtrated
  4. customdried

출처 및 근거

ORD 기록
ord-e12f6ba25a354dfba10ed06cd46129f0
출처 데이터셋
uspto-grants-1994_05
특허 번호
US05310920

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