Acrylic Acid → Oxan-2-yl prop-2-enoate

HRID 1034127

반응식

HRID 1034127 반응식
[C:1]([OH:5])(=[O:4])[CH:2]=[CH2:3].[O:6]1[CH:11]=[CH:10][CH2:9][CH2:8][CH2:7]1>ClCCl>[C:1]([O:5][CH:7]1[CH2:8][CH2:9][CH2:10][CH2:11][O:6]1)(=[O:4])[CH:2]=[CH2:3]

참가 물질

4

반응물 2

HCID 6581Acrylic AcidHCID 80803,4-dihydro-2H-pyran

생성물 1

HCID 21909470Oxan-2-yl prop-2-enoate수율 26%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of 10.5 g (146 mmol, 10 ml) acrylic acid and 14.0 g (166 mmol, 15.2 ml) dihydropyran in 40 ml dichloromethane was stirred at room temperature for one day. The mixture was washed with saturated aqueous sodium bicarbonate and the organic layer was concentrated in vacuo. The residue was distilled to give 5.93 g (38.0 mmol, 26% yield) tetrahydropyran-2-yl acrylate, bp 40° C. at 0.2 torr.

후처리

  1. washThe mixture was washed with saturated aqueous sodium bicarbonate
  2. concentrationthe organic layer was concentrated in vacuo
  3. distillationThe residue was distilled

출처 및 근거

ORD 기록
ord-1a9b6edd26bf4948b0ccb01a50c9bf06
출처 데이터셋
uspto-grants-1994_05
특허 번호
US05314785

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