3-Hydroxypyridine → 6-Methyl-2-(pyridin-3-yloxy)-nicotinonitrile

HRID 1035003

반응식

Cl[C:2]1[N:9]=[C:8]([CH3:10])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[N:11]1[CH:16]=[CH:15][CH:14]=[C:13]([OH:17])[CH:12]=1>>[CH3:10][C:8]1[CH:7]=[CH:6][C:3]([C:4]#[N:5])=[C:2]([O:17][C:13]2[CH:12]=[N:11][CH:16]=[CH:15][CH:14]=2)[N:9]=1

참가 물질

반응물 2

HCID 79713-Hydroxypyridine

HCID 5204002-Chloro-6-methylpyridine-3-carbonitrile

생성물 1

HCID 552074746-Methyl-2-(pyridin-3-yloxy)-nicotinonitrile

실험 절차

2-chloro-6-methyl-nicotinonitrile was reacted with pyridin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 212(M+1)+.

출처 및 근거

ORD 기록: ord-1c0a4c66e7844ecc8217d2b239da91e6
출처 데이터셋: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08546374B2

연결된 노트

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