Triethylamine → 2-methyl-6-[(3R)-3-methylpiperazin-1-yl]-3-{1-[(4-methylphenyl)sulphonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}imidazo[1,2-b]pyridazine

반응식

Cl[C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([C:12]3[CH:17]=[CH:16][N:15]=[C:14]4[N:18]([S:21]([C:24]5[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][CH:25]=5)(=[O:23])=[O:22])[CH:19]=[CH:20][C:13]=34)=[C:9]([CH3:11])[N:10]=2)[N:7]=1.[CH3:31][C@@H:32]1[CH2:37][NH:36][CH2:35][CH2:34][NH:33]1.C(N(CC)CC)C>C(O)CCCC.Cl>[CH3:11][C:9]1[N:10]=[C:5]2[CH:4]=[CH:3][C:2]([N:36]3[CH2:35][CH2:34][NH:33][C@H:32]([CH3:31])[CH2:37]3)=[N:7][N:6]2[C:8]=1[C:12]1[CH:17]=[CH:16][N:15]=[C:14]2[N:18]([S:21]([C:24]3[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][CH:25]=3)(=[O:23])=[O:22])[CH:19]=[CH:20][C:13]=12