Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-methyl-5-nitro-1H-indazole-3-carboxamide → 5-Amino-N-methyl-1H-indazole-3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-methyl-5-nitro-1H-indazole-3-carboxamide | HCID 45810073 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-Amino-N-methyl-1H-indazole-3-carboxamide | HCID 22567319 | 105.1% |
반응 단계
To a suspension of compound 55 (65 mg) in 5 mL of methanol was added catalytic amount of 5% palladium on carbon. The mixture was stirred under a hydrogen atmosphere at room temperature for 4 hrs and filtered through celite. The filtrate was concentrated to afford compound 56 (59 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08546404B2 |
| 출처 데이터셋 | uspto-grants-2013_10 |
| ORD ID | ord-7008f161220d40e19af52abfa231e6b5 |
| 출처 메모 | uspto-grants-2013_10 |