N,N-Diethyl-p-phenylenediamine → HCID 57710357, 화합물

반응식

Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][CH3:9])[CH:3]=1.[NH2:10][C:11]1[CH:21]=[CH:20][C:14]([N:15]([CH2:18][CH3:19])[CH2:16][CH3:17])=[CH:13][CH:12]=1>>[CH2:18]([N:15]([CH2:16][CH3:17])[C:14]1[CH:20]=[CH:21][C:11]([NH:10][C:2]2[CH:3]=[C:4]([NH:8][CH3:9])[N:5]=[CH:6][N:7]=2)=[CH:12][CH:13]=1)[CH3:19]

참가 물질

반응물 2

HCID 7120N,N-Diethyl-p-phenylenediamine

HCID 3094796-chloro-N-methylpyrimidin-4-amine

생성물 1

HCID 57710357HCID 57710357, 화합물

실험 절차

The title compound is prepared analogously as described in Example 105A from (6-chloro-pyrimidin-4-yl)-methyl-amine and 4-amino-N,N-diethylaniline. The ethyl acetate layer is dried over Na2SO4 and evaporated in vacuo. The residue is suspended in CH2Cl2, filtered off and dried to afford the title compound.

후처리

customThe title compound is prepared analogously
dry with materialThe ethyl acetate layer is dried over Na2SO4
customevaporated in vacuo
filtrationfiltered off
customdried

출처 및 근거

ORD 기록: ord-3c236ae5c4004f63a5ee7b8193ec5493
출처 데이터셋: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08552002B2

반응 노트

불러오는 중…