Phthalamide → 4-(4-(aminomethyl)-4-fluoropiperidin-1-yl)-N-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-6-yl)furo[3,2-d]pyrimidin-2-amine

반응식

[F:1][C:2]1([CH2:35][N:36]2C(=O)C3C(=CC=CC=3)C2=O)[CH2:7][CH2:6][N:5]([C:8]2[C:9]3[O:34][CH:33]=[CH:32][C:10]=3[N:11]=[C:12]([NH:14][C:15]3[CH:23]=[C:22]4[C:18]([CH:19]=[N:20][N:21]4[CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:31])([CH3:30])[CH3:29])=[CH:17][CH:16]=3)[N:13]=2)[CH2:4][CH2:3]1.C(N)(=O)C1C(=CC=CC=1)C(N)=O.ClC1N=C(Cl)C2OC=CC=2N=1.C[Si](C)(C)CCOCN1C2C(=CC=C(N)C=2)C=N1.O.NN>CO>[NH2:36][CH2:35][C:2]1([F:1])[CH2:7][CH2:6][N:5]([C:8]2[C:9]3[O:34][CH:33]=[CH:32][C:10]=3[N:11]=[C:12]([NH:14][C:15]3[CH:23]=[C:22]4[C:18]([CH:19]=[N:20][N:21]4[CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:31])([CH3:29])[CH3:30])=[CH:17][CH:16]=3)[N:13]=2)[CH2:4][CH2:3]1