Acetic Anhydride → HCID 58938508, 화합물

반응식

[NH2:1][C:2]1[C:7]([C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:9])=[CH:6][N:5]=[CH:4][N:3]=1.[C:17](OC(=O)C)(=O)[CH3:18]>>[CH3:17][C:18]1[N:10]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:8](=[O:9])[C:7]2[C:2]([N:1]=1)=[N:3][CH:4]=[N:5][CH:6]=2

참가 물질

반응물 2

HCID 7918Acetic Anhydride

HCID 58938487HCID 58938487, 화합물

생성물 1

HCID 58938508HCID 58938508, 화합물

반응 조건

온도: 120 °C

실험 절차

Compound 23 (70.0 mg, 0.32 mmol) was mixed with 6 mL of acetic anhydride and the reaction mixture was stirred at 120° C. for 2 h while monitored by MS. The reaction mixture was then concentrated in vacuo to yield 75 mg of crude compound 24 which was used for the next step without further purification.

후처리

concentrationThe reaction mixture was then concentrated in vacuo

출처 및 근거

ORD 기록: ord-4f9edf472b2749fd9f2e4ed09783173b
출처 데이터셋: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08552009B2

반응 노트

불러오는 중…