Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-nitro-2-(1H-1,2,4-triazol-1-yl)pyridine → 6-(1H-1,2,4-triazol-1-yl)pyridin-3-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-nitro-2-(1H-1,2,4-triazol-1-yl)pyridine | HCID 2766764 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 6-(1H-1,2,4-triazol-1-yl)pyridin-3-amine | HCID 16772327 | — |
반응 단계
5-nitro-2-(1H-1,2,4-triazol-1-yl)pyridine (100 mg, 0.523 mmol) from step 1 of this example was added Pd/C (111 mg, 0.105 mmol) and methanol (5.2 mL). Set the reaction on Parr Shaker at 50 psi (345 kPa) for overnight. The solution was filtered through CELITE and rinsed with methanol to give the title compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08552022B2 |
| 출처 데이터셋 | uspto-grants-2013_10 |
| ORD ID | ord-fbe714709af342a7b7b3c79361752d35 |
| 출처 메모 | uspto-grants-2013_10 |