Ethyl Acetate → HCID 55281286, 화합물

HRID 1039121

반응식

HRID 1039121 반응식
[NH:1]([C:3](=[S:6])OC)[NH2:2].[NH:7]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9][CH2:8]1.C(OCC)(=O)C>C(O)C>[NH:1]([C:3]([N:7]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9][CH2:8]1)=[S:6])[NH2:2]

참가 물질

5

반응물 3

HCID 8857Ethyl AcetateHCID 79341Piperidin-4-olHCID 10171237O-methyl hydrazinecarbothioate

생성물 1

HCID 55281286HCID 55281286, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
90 °C

실험 절차

A solution of methyl hydrazinecarbothioate (1.0 g, 8.2 mmol) and piperidin-4-ol (1.24 g, 12.3 mmol) in ethanol (7 mL) was refluxed with heating at 90° C. for 2 days. After addition of ethyl acetate, the reaction solution was washed with saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate and concentrated to give the crude desired product. The crude product was used directly for the next reaction.

후처리

  1. washthe reaction solution was washed with saturated aqueous sodium chloride
  2. dry with materialdried over anhydrous magnesium sulfate
  3. concentrationconcentrated

출처 및 근거

ORD 기록
ord-ffdf41338bfb4baf90c4987ed35a4d2c
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08552031B2

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