Homoserine lactone hydrobromide → 2-Amino-4-bromobutanoic acid hydrobromide

HRID 1040502

반응식

HRID 1040502 반응식
[BrH:1].[NH2:2][CH:3]1[CH2:8][CH2:7][O:6][C:4]1=[O:5]>Br.CC(O)=O>[BrH:1].[NH2:2][CH:3]([CH2:8][CH2:7][Br:1])[C:4]([OH:6])=[O:5]

참가 물질

4

반응물 1

HCID 73508Homoserine lactone hydrobromide

생성물 1

HCID 138779922-Amino-4-bromobutanoic acid hydrobromide수율 64%

시약·촉매·용매 2

HCID 176Acetic Acid용매HCID 260Hydrogen Bromide용매

반응 조건

온도
100 °C

실험 절차

A suspension of α-amino-γ-butyrolactone hydrobromide in 30% HBr in HOAc was heated at 100° C. in a sealed tube for 5 days. The mixture was concentrated to give a white solid that was washed with Et2O to provide 23.1 g (64%) of 2-amino-4-bromo-butyric acid hydrobromide.

후처리

  1. concentrationThe mixture was concentrated
  2. customto give a white solid
  3. washthat was washed with Et2O

출처 및 근거

ORD 기록
ord-f38f179cf9dd4131a13e1590a509ceb1
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08552205B2

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