1,2-Dichloroethane → 6-Amino-2-[bis(carboxymethyl)amino]hexanoic acid

HRID 1041821

반응식

HRID 1041821 반응식
C(Cl)CCl.[CH2:5]([CH2:9][C@H:10]([N:14]([CH2:19][C:20]([OH:22])=[O:21])[CH2:15][C:16]([OH:18])=[O:17])[C:11]([OH:13])=[O:12])[CH2:6][CH2:7][NH2:8]>CS(C)=O>[NH2:8][CH2:7][CH2:6][CH2:5][CH2:9][CH:10]([N:14]([CH2:19][C:20]([OH:22])=[O:21])[CH2:15][C:16]([OH:18])=[O:17])[C:11]([OH:13])=[O:12]

참가 물질

4

반응물 2

HCID 111,2-DichloroethaneHCID 7019830N-(5-Amino-1-carboxypentyl)iminodiacetic acid

생성물 1

HCID 27352966-Amino-2-[bis(carboxymethyl)amino]hexanoic acid

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매2회

실험 절차

A solution was prepared by the addition of 1 mmol of EDC and 0.2 mmol of NHS to 1 ml of DMSO, and 50 μl of the thus prepared solution was added onto the CMD film. The solution was then allowed to undergo the reaction at the room temperature for 30 minutes. After the solution was removed, washing with DMSO was performed one time. Also, a solution prepared by the addition of 0.1 mmol of AB-NTA (supplied by Dojin Kagaku K.K.) to 1 ml of DMSO was allowed to undergo the reaction for 12 hours. The solution was removed, and washing with ultra pure water was performed one time.

후처리

  1. additionwas added onto the CMD film
  2. customthe reaction at the room temperature for 30 minutes
  3. customAfter the solution was removed
  4. washwashing with DMSO
  5. customthe reaction for 12 hours
  6. customThe solution was removed
  7. washwashing with ultra pure water

출처 및 근거

ORD 기록
ord-875e695d231845f9836da25fe77b3704
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08557194B2

연결된 노트

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