2-Hydrazinyl-4-iodopyridine → HCID 178453093, 화합물

HRID 1041961

반응식

HRID 1041961 반응식
[CH:1]([C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[C:6]([N:13]3[CH2:18][CH2:17][CH:16]([CH2:19][NH:20][C:21](=[O:27])[O:22][C:23]([CH3:26])([CH3:25])[CH3:24])[CH2:15][CH2:14]3)[CH:7]=[CH:8][CH:9]=2)[N:4]=1)=O.[I:28][C:29]1[CH:34]=[CH:33][N:32]=[C:31]([NH:35][NH2:36])[CH:30]=1>C(Cl)Cl>[I:28][C:29]1[CH:34]=[CH:33][N:32]=[C:31]([NH:35]/[N:36]=[CH:1]/[C:3]2[CH:12]=[CH:11][C:10]3[C:5](=[C:6]([N:13]4[CH2:14][CH2:15][CH:16]([CH2:19][NH:20][C:21](=[O:27])[O:22][C:23]([CH3:25])([CH3:26])[CH3:24])[CH2:17][CH2:18]4)[CH:7]=[CH:8][CH:9]=3)[N:4]=2)[CH:30]=1

참가 물질

4

반응물 2

HCID 534028972-Hydrazinyl-4-iodopyridineHCID 86654345Tert-butyl (1-(2-formylquinolin-8-yl)piperidin-4-yl)methylcarbamate

생성물 1

HCID 178453093HCID 178453093, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To tert-butyl (1-(2-formylquinolin-8-yl)piperidin-4-yl)methylcarbamate (112 mg, 0.303 mmol) in DCM (20 mL) was added 1-(4-iodopyridin-2-yl)hydrazine (78.4 mg, 0.333 mmol). The reaction mixture was stirred for 1 hour and then taken on to directly to the next step.

출처 및 근거

ORD 기록
ord-07166c0a1907496e8a191a1a6137e0bf
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08557809B2

연결된 노트

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