Lithium Hydroxide → 3-(2-Butoxy-4-trifluoromethyl-phenyl)-acrylic acid
반응식
C[O:2][C:3](=[O:21])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:7]=1[O:16][CH2:17][CH2:18][CH2:19][CH3:20].[Li+].[OH-]>C1COCC1.CO>[CH2:17]([O:16][C:7]1[CH:8]=[C:9]([C:12]([F:14])([F:13])[F:15])[CH:10]=[CH:11][C:6]=1[CH:5]=[CH:4][C:3]([OH:21])=[O:2])[CH2:18][CH2:19][CH3:20]참가 물질
5
실험 절차
3-(2-Butoxy-4-trifluoromethyl-phenyl)-acrylic acid methyl ester (464 mg) was reacted with 1N LiOH (10 ml) in THF and CH3OH for 1 hr as described above to yield title compound
출처 및 근거
- ORD 기록
- ord-5ea66f13bf564d94a4c264b6185475b5
- 출처 데이터셋
- uspto-grants-2013_10
- 특허 번호
- US08557872B2
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