Iodoethane → 9-[(1-Ethyl-4-piperidinyl)methyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine
반응식
[CH2:1]([N:3]1[CH2:8][CH2:7]C[CH:5]([CH2:9][CH2:10][N:11]2[C:19]([O:20][CH3:21])=[N:18][C:17]3[C:12]2=[N:13][C:14]([O:23][C@@H:24]([CH3:28])[CH2:25][CH2:26][CH3:27])=[N:15][C:16]=3[NH2:22])[CH2:4]1)[CH3:2].C[C@H](OC1N=C2C(N=C(OC)N2CC2CCNCC2)=C(N)N=1)CCC.ICC>>[CH2:1]([N:3]1[CH2:4][CH2:5][CH:9]([CH2:10][N:11]2[C:19]([O:20][CH3:21])=[N:18][C:17]3[C:12]2=[N:13][C:14]([O:23][C@@H:24]([CH3:28])[CH2:25][CH2:26][CH3:27])=[N:15][C:16]=3[NH2:22])[CH2:7][CH2:8]1)[CH3:2]참가 물질
4
반응물 3
생성물 1
실험 절차
Prepared similarly to Intermediate 46 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9-(4-piperidinylmethyl)-9H-purin-6-amine and iodoethane.
출처 및 근거
- ORD 기록
- ord-576219dac32f4326a0b5923222a65ba4
- 출처 데이터셋
- uspto-grants-2013_10
- 특허 번호
- US08563717B2
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