1-Bromo-3-methylbutane → 6-Amino-2-(butyloxy)-9-{2-[1-(3-methylbutyl)-4-piperidinyl]ethyl}-7,9-dihydro-8H-purin-8-one
반응식
[CH2:1]([O:5][C:6]1[N:14]=[C:13]2[C:9]([N:10]=[C:11]([O:23]C)[N:12]2[CH2:15][CH2:16][CH:17]2[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]2)=[C:8]([NH2:25])[N:7]=1)[CH2:2][CH2:3][CH3:4].Br[CH2:27][CH2:28][CH:29]([CH3:31])[CH3:30]>>[NH2:25][C:8]1[N:7]=[C:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])[N:14]=[C:13]2[C:9]=1[NH:10][C:11](=[O:23])[N:12]2[CH2:15][CH2:16][CH:17]1[CH2:18][CH2:19][N:20]([CH2:27][CH2:28][CH:29]([CH3:31])[CH3:30])[CH2:21][CH2:22]1참가 물질
3
실험 절차
Prepared similarly to Example 80 from 2-(butyloxy)-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amine and 1-bromo-3-methylbutane.
출처 및 근거
- ORD 기록
- ord-b84b919685bf43b38a8848e1ac5fb138
- 출처 데이터셋
- uspto-grants-2013_10
- 특허 번호
- US08563717B2
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