참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | m-Toluidine | HCID 7934 | — |
| 반응물 | 3-Phenylprop-2-enoyl chloride | HCID 66023 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3'-Methylcinnamanilide | HCID 583018 | — |
반응 단계
m-Toluidine (5 g, 46.64 mmol) and pyridine (3.77 mL, 46.64 mmol) were dissolved in dry dichloromethane (25 mL). To the reaction mixture, cinnamoyl chloride (7.72 g, 46.64 mmol) was added and stirred for 3 h at 0° C. The reaction mixture was extracted with dichloromethane washing with water and 2N HCl. The solvent was removed and the crude product was used in the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08569282B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_10 |
|---|
| ORD ID | ord-14ca28f2f70a417195f49f94d34eea8b |
|---|
| 출처 메모 | uspto-grants-2013_10 |
|---|
