5-Nitro-3-(trifluoromethyl)-2-pyridinecarbonitrile → 5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile

HRID 1051122노트

반응식

HRID 1051122 반응식
[C:1]([C:3]1[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][C:6]([N+:13]([O-])=O)=[CH:5][N:4]=1)#[N:2].[H][H]>[Ni]>[C:1]([C:3]1[C:8]([C:9]([F:12])([F:10])[F:11])=[CH:7][C:6]([NH2:13])=[CH:5][N:4]=1)#[N:2]

참가 물질

4

반응물 2

HCID 218748935-Nitro-3-(trifluoromethyl)-2-pyridinecarbonitrileHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 135322465-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

Alternatively, 2-cyano-3-(trifluoromethyl)-5-nitropyridine A10 can be reacted with hydrogen over Raney-Ni to obtain 2-cyano-3-(trifluoromethyl)-5-aminopyridine, A11.

출처 및 근거

ORD 기록
ord-a6e0b2faec4d4376bbd5b8d381ee569a
출처 데이터셋
uspto-grants-2016_07
특허 번호
US09388159B2

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