Pyrrolidine → (4-Bromo-3-methoxyphenyl)(pyrrolidin-1-yl)methanone

HRID 1051853노트

반응식

HRID 1051853 반응식
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[CH:4][C:3]=1[O:11][CH3:12].[NH:13]1[CH2:17][CH2:16][CH2:15][CH2:14]1>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)=[O:8])=[CH:4][C:3]=1[O:11][CH3:12]

참가 물질

3

반응물 2

HCID 31268PyrrolidineHCID 162158674-Bromo-3-methoxybenzoic acid

생성물 1

HCID 71412413(4-Bromo-3-methoxyphenyl)(pyrrolidin-1-yl)methanone

실험 절차

Starting with 4-bromo-3-methoxybenzoic acid and pyrrolidine, Int02.07 was prepared analogously to the procedure for the preparation of Int02.04.

후처리

  1. customwas prepared analogously to the procedure for the preparation of Int02.04

출처 및 근거

ORD 기록
ord-552658d35b224dd4a9bce653467c5ae3
출처 데이터셋
uspto-grants-2016_07
특허 번호
US09388177B2

반응 노트

불러오는 중…