참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methyl 3-bromobenzoate | HCID 12070 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | m-Bromobenzohydrazide | HCID 520941 | 90% |
반응 단계
Methyl 3-bromobenzoate (2 g, 9.3 mmol) was dissolved in 25 ml ethanol. Hydrazine hydrate (4.5 ml, 92.9 mmol) was added and the reaction was stirred at 80° C. overnight. The reaction mixture was evaporated under reduced pressure and a white solid was formed. This solid was washed with water and diethyl ether and dried in the vacuum oven to afford 1.8 g (90% yield) of the title compound. Purity 100%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09388189B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_07 |
|---|
| ORD ID | ord-c5dec2be34f44a01b83b9a791a8ab349 |
|---|
| 출처 메모 | uspto-grants-2016_07 |
|---|
