反应详情

温度

80 °C

Methyl 3-bromobenzoate (2 g, 9.3 mmol) was dissolved in 25 ml ethanol. Hydrazine hydrate (4.5 ml, 92.9 mmol) was added and the reaction was stirred at 80° C. overnight. The reaction mixture was evaporated under reduced pressure and a white solid was formed. This solid was washed with water and diethyl ether and dried in the vacuum oven to afford 1.8 g (90% yield) of the title compound. Purity 100%.

1. customThe reaction mixture was evaporated under reduced pressure
2. customa white solid was formed
3. washThis solid was washed with water and diethyl ether
4. customdried in the vacuum oven