N-bromobutanimide → 2-Bromo-3-(bromomethyl)pyridine

HRID 1054039노트

반응식

HRID 1054039 반응식
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][N:3]=1.C1C(=O)N([Br:16])C(=O)C1>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[C:7]([CH2:8][Br:16])=[CH:6][CH:5]=[CH:4][N:3]=1

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 2208322-Bromo-3-methylpyridine

생성물 1

HCID 109010782-Bromo-3-(bromomethyl)pyridine

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

Synthesized from 2-bromo-3-methylpyridine (5.00 g, 29.1 mmol), NBS (5.69 g, 32.0 mmol) and DBPO (352 mg, 1.46 mmol) in CCl4 according to Method A. Yield: 2.87 g, 11.4 mmol, 39%. This compound was directly used in the next step without further purification.

후처리

  1. customThis compound was directly used in the next step without further purification

출처 및 근거

ORD 기록
ord-6d31b88bbc234e6da3ea61156b70d883
출처 데이터셋
uspto-grants-2016_07
특허 번호
US09394290B2

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