Iodine → HCID 178471365, 화합물

HRID 1055182

반응식

HRID 1055182 반응식
[Zn:1].II.[Br:4]CCCCCCCCC(OCC)=O.[C:18]([O:28][CH2:29][CH3:30])(=[O:27])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>CC(N(C)C)=O>[Br:4][Zn:1][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][C:18]([O:28][CH2:29][CH3:30])=[O:27]

참가 물질

6

반응물 4

HCID 807Iodine2회HCID 23994Zinc2회HCID 31251Ethyl NonanoateHCID 560317Disodium acetylide

생성물 1

HCID 178471365HCID 178471365, 화합물

시약·촉매·용매 1

HCID 31374Dimethylacetamide용매

반응 조건

온도
80 °C

실험 절차

In a dry reaction tube under nitrogen were charged zinc dust (3.70 g, 56.6 mmol), iodine (479 mg, 1.89 mmol) and dry DMA (20 mL). The mixture was stirred at room temperature until the color of iodine disappeared. Ethyl 9-bromononanoate was added, and the mixture was stirred at 80° C. for 4 hours and then at room temperature overnight. (Completion of the zinc insertion reaction was checked by GCMS analysis of the hydrolyzed reaction mixture.) The reaction mixture was used without further treatment in the subsequent step. GCMS m/z 186 [M]+ (ethyl nonanoate).

후처리

  1. customIn a dry reaction tube under nitrogen
  2. customat room temperature
  3. customovernight

출처 및 근거

ORD 기록
ord-0ef785149a124889a3ddb5d4f53c3659
출처 데이터셋
uspto-grants-2016_07
특허 번호
US09393315B2

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