HCID 54513511, 화합물 → 4-Isopropyloxy-2-methylpyridine

HRID 1059869노트

반응식

HRID 1059869 반응식
[CH:1]([O:4][C:5]1[CH:10]=[CH:9][N+:8]([O-])=[C:7]([CH3:12])[CH:6]=1)([CH3:3])[CH3:2]>CC(O)C.[Ni]>[CH:1]([O:4][C:5]1[CH:10]=[CH:9][N:8]=[C:7]([CH3:12])[CH:6]=1)([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 54513511HCID 54513511, 화합물

생성물 1

HCID 186675734-Isopropyloxy-2-methylpyridine수율 78.7%

시약·촉매·용매 2

HCID 935Nickel촉매HCID 3776Isopropanol용매

실험 절차

A suspension of 4-isopropyloxy-2-methylpyridine N-oxide (0.78 g) in 2-propanol (10 ml) was hydrogenated over Raney-nickel (50% suspension in water, 1 ml) under a hydrogen atmosphere for 48 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 4-isopropyloxy-2-methylpyridine (555 mg).

후처리

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-5308d304416e473dab3b9bf7ec755edf
출처 데이터셋
uspto-grants-2003_02
특허 번호
US06521643B1

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