(4-Furan-2-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester → (2-Amino-4-furan-2-yl-phenyl)-carbamic acid tert.-butyl ester

HRID 1061955노트

반응식

HRID 1061955 반응식
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[O:15][CH:16]=[CH:17][CH:18]=2)=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[O:15][CH:16]=[CH:17][CH:18]=2)=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 1

HCID 69592762(4-Furan-2-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester

생성물 1

HCID 69592822(2-Amino-4-furan-2-yl-phenyl)-carbamic acid tert.-butyl ester

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

Prepared from (4-furan-2-yl-2-nitrophenyl)-carbamic acid tert.-butyl ester (Example B3) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a grey powder (212 mg).

출처 및 근거

ORD 기록
ord-cb3faa1f6afc46a085f24ae22bb8829f
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06960578B2

반응 노트

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