1-Naphthol → HCID 2848155, 화합물

HRID 1063098노트

반응식

HRID 1063098 반응식
[C:1]1([OH:11])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.Cl.Cl[CH2:14][CH2:15][N:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1.[OH-].[Na+]>C(O)C>[C:1]1([O:11][CH2:14][CH2:15][N:16]2[CH2:21][CH2:20][O:19][CH2:18][CH2:17]2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 70051-NaphtholHCID 14798Sodium HydroxideHCID 77210Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)

생성물 1

HCID 2848155HCID 2848155, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

441 g of 1-naphthol and 648 g of N-(2-chloroethyl)morpholine hydrochloride are initially charged in 2680 ml of ethanol at 50° C. 554 g of 50% aqueous sodium hydroxide are added dropwise within 3 h. Stirring is then continued at 50° C. for 3 h and then for 1 h under reflux.

후처리

  1. temperaturefor 1 h under reflux

출처 및 근거

ORD 기록
ord-9d617cb69ed241d7ba661f9c76679dc0
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06964963B2

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